Literature DB >> 4479306

The possible role of cytochrome P-450 in the liver "first pass elimination" of a beta-receptor blocking drug.

R Grundin, P Moldéus, S Orrenius, K O Borg, I Skånberg, C von Bahr.   

Abstract

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Year:  1974        PMID： 4479306     DOI： 10.1111/j.1600-0773.1974.tb00744.x

Source DB:  PubMed          Journal:  Acta Pharmacol Toxicol (Copenh)        ISSN： 0001-6683


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  8 in total

1.  Importance of "first-pass elimination" for interindividual differences in steady-state concentrations of the adrenergic beta-receptor antagonist alprenolol.

Authors:  G Alván; M Lind; B Mellström; C von Bahr
Journal:  J Pharmacokinet Biopharm       Date:  1977-06

2.  Decreased plasma concentrations and clinical effects of alprenolol during combined treatment with pentobarbitone in hypertension.

Authors:  P Seideman; K O Borg; K Haglund; C Von Bahr
Journal:  Br J Clin Pharmacol       Date:  1987-03       Impact factor: 4.335

Review 3.  Clinical pharmacokinetics of beta-adrenoreceptor blocking drugs.

Authors:  G Johnsson; C G Regàrdh
Journal:  Clin Pharmacokinet       Date:  1976       Impact factor: 6.447

4.  The effect of chlorpromazine, metyrapone, imipramine and SKF 525-A on the hepatic first pass elimination of propranolol in the pithed rat.

Authors:  H E Barber; N R Kitteringham; J C Petrie
Journal:  Br J Pharmacol       Date:  1982-12       Impact factor: 8.739

5.  Bioavailability of metoprolol in young adults and the elderly, with additional studies on the effects of metoclopramide and probanthine.

Authors:  R H Briant; R E Dorrington; D G Ferry; J W Paxton
Journal:  Eur J Clin Pharmacol       Date:  1983       Impact factor: 2.953

6.  Correlation between in vitro and in vivo drug metabolism rate: oxidation of ethoxybenzamide in rat.

Authors:  J H Lin; M Hayashi; S Awazu; M Hanano
Journal:  J Pharmacokinet Biopharm       Date:  1978-08

7.  First pass hydroxylation of nortriptyline: concentrations of parent drug and major metabolites in plasma.

Authors:  G Alván; O Borga; M Lind; L Palmér; B Siwers
Journal:  Eur J Clin Pharmacol       Date:  1977-03-11       Impact factor: 2.953

8.  Pharmacokinetics and pharmacodynamics of propranolol stereoisomers in hyperthyroid patients.

Authors:  K Tawara; K Kawashima; H Ishikawa; K Yamamoto; K Saito; A Ebihara; S Yoshida
Journal:  Eur J Clin Pharmacol       Date:  1981-02       Impact factor: 2.953
  8 in total

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