Literature DB >> 446651

Ketoconazole -- a new broad spectrum orally active antimycotic.

D Thienpont, J Van Cutsem, F Van Gerven, J Heeres, P A Janssen.   

Abstract

Oral treatment with ketoconazole prevented and cured artificial crop candidosis of the turkey, vaginal candidosis of the rat and skin candidosis of the guinea-pig. It was also highly effective against artificial systemic candidosis of the guinea-pig and chicken as well as against dermatophytoses of the guinea-pig.

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Year:  1979        PMID： 446651     DOI： 10.1007/bf01960348

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


  4 in total

1.  Miconazole, a broad-spectrum antimycotic agent with antibacterial activity.

Authors:  J M Van Cutsem; D Thienpont
Journal:  Chemotherapy       Date:  1972       Impact factor: 2.544

2.  The preparation and antimycotic properties of derivatives of 1-phenethylimidazole.

Authors:  E F Godefroi; J Heeres; J Van Cutsem; P A Janssen
Journal:  J Med Chem       Date:  1969-09       Impact factor: 7.446

3.  Experimental cutaneous Candida albicans infection in guinea-pigs.

Authors:  J Van Cutsem; D Thienpont
Journal:  Sabouraudia       Date:  1971-03

4.  Synthesis and antimyoctic properties of 1-(2-alkyl-2-phenylethyl)-1H-imidazoles.

Authors:  J Heeres; L J Backx; J M Van Cutsem
Journal:  J Med Chem       Date:  1976-09       Impact factor: 7.446
  4 in total
  19 in total

Review 1.  An overview of topical antifungal therapy in dermatomycoses. A North American perspective.

Authors:  A K Gupta; T R Einarson; R C Summerbell; N H Shear
Journal:  Drugs       Date:  1998-05       Impact factor: 9.546

2.  Activity of SM-4470, a new imidazole derivative, against experimental fungal infections.

Authors:  K Ichise; T Tanio; I Saji; T Okuda
Journal:  Antimicrob Agents Chemother       Date:  1986-09       Impact factor: 5.191

Review 3.  The endocrine effects of ketoconazole.

Authors:  N Sonino
Journal:  J Endocrinol Invest       Date:  1986-08       Impact factor: 4.256

Review 4.  Overview of medically important antifungal azole derivatives.

Authors:  R A Fromtling
Journal:  Clin Microbiol Rev       Date:  1988-04       Impact factor: 26.132

Review 5.  Ketoconazole: a review of its therapeutic efficacy in superficial and systemic fungal infections.

Authors:  R C Heel; R N Brogden; A Carmine; P A Morley; T M Speight; G S Avery
Journal:  Drugs       Date:  1982 Jan-Feb       Impact factor: 9.546

6.  Enhancement of ketoconazole penetration across the blood-brain barrier of mice by dimethyl sulfoxide.

Authors:  P C Iwen; N G Miller
Journal:  Antimicrob Agents Chemother       Date:  1986-10       Impact factor: 5.191

7.  Entry of ketoconazole into Candida albicans.

Authors:  P Boiron; E Drouhet; B Dupont; L Improvisi
Journal:  Antimicrob Agents Chemother       Date:  1987-02       Impact factor: 5.191

8.  In vitro and in vivo effects of the antimycotic drug ketoconazole on sterol synthesis.

Authors:  H Van den Bossche; G Willemsens; W Cools; F Cornelissen; W F Lauwers; J M van Cutsem
Journal:  Antimicrob Agents Chemother       Date:  1980-06       Impact factor: 5.191

9.  Effects of the combination of metyrapone and oxazepam on cocaine and food self-administration in rats.

Authors:  Nicholas E Goeders; Glenn F Guerin
Journal:  Pharmacol Biochem Behav       Date:  2008-07-19       Impact factor: 3.533

10.  Combined activity of ketoconazole and 5-fluorocytosine on potentially pathogenic yeasts.

Authors:  W H Beggs; G A Sarosi
Journal:  Antimicrob Agents Chemother       Date:  1982-02       Impact factor: 5.191
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