Literature DB >> 4462060

Assessment of an in vitro screening test of cytotoxic agents in the treatment of advanced malignant disease.

T K Wheeler, P P Dendy, A Dawson.   

Abstract

The value of a screening test for sytoxic chemotherapeutic agents in the treatment of advanced malignant disease is assessed by comparing the performances of 32 patients whose treatment followed closely the test recommendations with that of 31 patients whose treatment did not follow the predictions. The significant improvement in short-term prognosis (p=0.004) indicates that the test is of clinical value. The limitations of retrospective analysis are discussed in detail.

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Year:  1974        PMID: 4462060     DOI: 10.1159/000224977

Source DB:  PubMed          Journal:  Oncology        ISSN: 0030-2414            Impact factor:   2.935


  6 in total

Review 1.  Cellular drug resistance in childhood leukemia.

Authors:  A J Veerman; G J Kaspers; R Pieters
Journal:  Ann Hematol       Date:  1994       Impact factor: 3.673

2.  Effects of cytotoxic agents on TdR incorporation and growth delay in human colonic tumour xenografts.

Authors:  P J Houghton; J A Houghton; D M Taylor
Journal:  Br J Cancer       Date:  1977-08       Impact factor: 7.640

3.  British Association for Cancer Research 22nd Annual general meeting. 13-15 April 1981. Abstracts.

Authors: 
Journal:  Br J Cancer       Date:  1981-08       Impact factor: 7.640

4.  A comparison of three assays used for the in vitro chemosensitivity testing of human tumours.

Authors:  A P Wilson; C H Ford; C E Newman; A Howell
Journal:  Br J Cancer       Date:  1984-01       Impact factor: 7.640

5.  Fractional incorporation of [3H]thymidine and DNA specific activity as assays of inhibition of tumour growth.

Authors:  P J Houghton; D M Taylor
Journal:  Br J Cancer       Date:  1977-01       Impact factor: 7.640

6.  In vitro sensitivity of human ovarian tumours to chemotherapeutic agents.

Authors:  A P Wilson; F E Neal
Journal:  Br J Cancer       Date:  1981-08       Impact factor: 7.640

  6 in total

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