Literature DB >> 4458670

Studies on the mechanism of formation of 5-mercapto-1-methyl-4-nitroimidazole, a metabolite of the immunosuppressive drug azathioprine.

A H Chalmers.   

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Year:  1974        PMID: 4458670     DOI: 10.1016/0006-2952(74)90198-1

Source DB:  PubMed          Journal:  Biochem Pharmacol        ISSN: 0006-2952            Impact factor:   5.858


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  13 in total

Review 1.  The clinical pharmacology of 6-mercaptopurine.

Authors:  L Lennard
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

Review 2.  Review article: The pharmacokinetics and pharmacodynamics of drugs used in inflammatory bowel disease treatment.

Authors:  E G Quetglas; A Armuzzi; S Wigge; G Fiorino; L Barnscheid; M Froelich; Silvio Danese
Journal:  Eur J Clin Pharmacol       Date:  2015-05-27       Impact factor: 2.953

Review 3.  Immunosuppressive drugs in inflammatory bowel disease. A review of their mechanisms of efficacy and place in therapy.

Authors:  A B Hawthorne; C J Hawkey
Journal:  Drugs       Date:  1989-08       Impact factor: 9.546

4.  Azathioprine pharmacokinetics after intravenous, oral, delayed release oral and rectal foam administration.

Authors:  E C Van Os; B J Zins; W J Sandborn; D C Mays; W J Tremaine; D W Mahoney; A R Zinsmeister; J J Lipsky
Journal:  Gut       Date:  1996-07       Impact factor: 23.059

5.  Effects of azathioprine on the human mixed lymphocyte reaction (MLR).

Authors:  S A Al-Safi; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1983-02       Impact factor: 4.335

6.  Azathioprine-related myelosuppression in a patient homozygous for TPMT*3A.

Authors:  Pooja Budhiraja; Mordecai Popovtzer
Journal:  Nat Rev Nephrol       Date:  2011-06-28       Impact factor: 28.314

7.  Clinical significance of azathioprine active metabolite concentrations in inflammatory bowel disease.

Authors:  S Wright; D S Sanders; A J Lobo; L Lennard
Journal:  Gut       Date:  2004-08       Impact factor: 23.059

8.  Azathioprine and 6-mercaptopurine (6-MP) suppress the human mixed lymphocyte reaction (MLR) by different mechanisms.

Authors:  S A Al-Safi; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1984-04       Impact factor: 4.335

9.  Azathioprine suppresses the mixed lymphocyte reaction of patients with Lesch-Nyhan syndrome.

Authors:  P W Szawlowski; S A Al-Safi; T Dooley; J L Maddocks
Journal:  Br J Clin Pharmacol       Date:  1985-11       Impact factor: 4.335

10.  Thiopurine S-methyltransferase activity in three major Asian populations: a population-based study in Singapore.

Authors:  Shirley Kow Yin Kham; Chin Kok Soh; Te Chih Liu; Yiong Huak Chan; Hany Ariffin; Poh Lin Tan; Allen Eng Juh Yeoh
Journal:  Eur J Clin Pharmacol       Date:  2008-01-11       Impact factor: 2.953

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