Literature DB >> 4406277

Public health and genetic constitution of the San ("Bushmen"): carbohydrate metabolism and acetylator status of the Kung of Tsumkwe in the North-western Kalahari.

T Jenkins, H Lehmann, G T Nurse.   

Abstract

Intolerance to lactose owing to deficiency of lactase is particularly prevalent among non-Caucasian peoples. Special caution is therefore needed in offering them milk supplements. Lactose tolerance has been investigated among the!Kung in the north-western Kalahari. The opportunity was taken also to examine their acetylator status, as this affects their ability to detoxicate drugs given for the treatment of tuberculosis and other diseases.The preliminary studies reported here suggest that not more than 10% of the!Kung are tolerant to lactose, but only one person out of 30 was a slow acetylator.

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Year:  1974        PMID: 4406277      PMCID: PMC1610132          DOI: 10.1136/bmj.2.5909.23

Source DB:  PubMed          Journal:  Br Med J        ISSN: 0007-1447


  20 in total

1.  The nutrient composition and dietary importance of some vegetable foods eaten by the Kung Bushmen.

Authors:  A S Wehmeyer; R B Lee; M Whiting
Journal:  S Afr Med J       Date:  1969-12-20

2.  Human variability in the metabolism of sulfamethazine.

Authors:  J M Parker
Journal:  Hum Hered       Date:  1969       Impact factor: 0.444

3.  An improved and simplified method of detecting the acetylator phenotype.

Authors:  D A Evans
Journal:  J Med Genet       Date:  1969-12       Impact factor: 6.318

4.  Lactose malabsorption in Greenland Eskimos.

Authors:  E Gudmand-Hoyer; S Jarnum
Journal:  Acta Med Scand       Date:  1969-09

5.  Defects of sugar absorption. Sugar malabsorption and sugar intolerance in childhood.

Authors:  A Holzel
Journal:  Proc R Soc Med       Date:  1968-11

6.  Lactose intolerance in South American Indians.

Authors:  H Alzate; H González; J Guzmán
Journal:  Am J Clin Nutr       Date:  1969-02       Impact factor: 7.045

7.  Lactose deficiency in the South African Bantu.

Authors:  J Jersky; R H Kinsley
Journal:  S Afr Med J       Date:  1967-12-16

8.  A racial difference in incidence of lactase deficiency. A survey of milk intolerance and lactase deficiency in healthy adult males.

Authors:  T M Bayless; N S Rosensweig
Journal:  JAMA       Date:  1966-09-19       Impact factor: 56.272

9.  Jejunal disaccharidases and some observations on the cause of lactase deficiency.

Authors:  H B McMichael; J Webb; A M Dawson
Journal:  Br Med J       Date:  1966-10-29

10.  N-acetylation of drugs: isolation and properties of an N-acetyltransferase from rabbit liver.

Authors:  W W Weber; S N Cohen
Journal:  Mol Pharmacol       Date:  1967-05       Impact factor: 4.436

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  2 in total

Review 1.  The geographic hypothesis and lactose malabsorption. A weighing of the evidence.

Authors:  F J Simoons
Journal:  Am J Dig Dis       Date:  1978-11

2.  Human acetylator polymorphism: estimate of allele frequency in Libya and details of global distribution.

Authors:  A K Karim; M S Elfellah; D A Evans
Journal:  J Med Genet       Date:  1981-10       Impact factor: 6.318

  2 in total

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