| Literature DB >> 440416 |
A Royal, A Garapin, B Cami, F Perrin, J L Mandel, M LeMeur, F Brégégègre, F Gannon, J P LePennec, P Chambon, P Kourilsky.
Abstract
Two large DNA fragments overlapping the chicken ovalbumin gene have been isolated by molecular cloning. Analysis of these fragments provided a map of a 46,000-base pair region of the chicken genome. This region contains the complete ovalbumin gene (including its mRNA leader-coding sequence) and at least two other genes of unknown function. All three genes are orientated in the same direction and their expression in chicken oviduct is under hormonal control. The three genes share some sequence homologies, suggesting that duplications have occurred in the ovalbumin gene region in the course of evolution.Entities:
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Year: 1979 PMID: 440416 DOI: 10.1038/279125a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962