| Literature DB >> 4395204 |
M S Hirsch, P H Black, G S Tracy, S Leibowitz, R S Schwartz.
Abstract
Young adult (BALB/c x A/J)F(1) hybrid mice have no detectable leukemia viruses. When inoculated with parental BALB/c spleen lymphoid cells, also free of detectable virus, leukemia viruses rapidly become activated in the injected host. Because of similarities between such graft-induced allogeneic disease and spontaneous autoimmunity, it is proposed that autoimmune reactions may activate latent viruses.Entities:
Mesh:
Year: 1970 PMID: 4395204 PMCID: PMC283447 DOI: 10.1073/pnas.67.4.1914
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205