Literature DB >> 4379260

Combined biochemical and morphological study of particulate fractions from rat liver. Analysis of preparations enriched in lysosomes or in particles containing urate oxidase, D-amino acid oxidase, and catalase.

P Baudhuin, H Beaufay, C De Duve.   

Abstract

Six particulate preparations isolated from rat liver under different experimental conditions were analyzed biochemically and examined in the electron microscope. The results confirm the lysosomal nature of the pericanalicular dense bodies and demonstrate that the microbodies are the bearers of urate oxidase, catalase, and D-amino acid oxidase. Catalase, representing a major component of the particles, and D-amino acid oxidase appear to be associated with the structureless "sap" of the particles, urate oxidase with their crystalloid core or with their outer membrane.

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Year:  1965        PMID: 4379260      PMCID: PMC2106697          DOI: 10.1083/jcb.26.1.219

Source DB:  PubMed          Journal:  J Cell Biol        ISSN: 0021-9525            Impact factor:   10.539


  21 in total

1.  ELECTRON MICROSCOPIC OBSERVATIONS ON THE LOCALIZATION OF ACID PHOSPHATASE IN MOUSE HEPATIC PARENCHYMAL CELLS.

Authors:  B F TRUMP; J L ERICSSON
Journal:  Exp Cell Res       Date:  1964-02       Impact factor: 3.905

2.  [Not Available].

Authors:  C ROUILLER
Journal:  C R Seances Soc Biol Fil       Date:  1954-12

3.  [An electron microscopic examination of purified fractions of cytoplasmic organites of rat liver].

Authors:  P BAUDHUIN; H BEAUFAY
Journal:  Arch Int Physiol Biochim       Date:  1963-01

4.  Tissue fractionation studies. 12. Intracellular distribution of some dehydrogenases, alkaline deoxyribonuclease and iron in rat-liver tissue.

Authors:  H BEAUFAY; D S BENDALL; P BAUDHUIN; C DE DUVE
Journal:  Biochem J       Date:  1959-12       Impact factor: 3.857

5.  The liver cell. Some new approaches to its study.

Authors:  A B NOVIKOFF; E ESSNER
Journal:  Am J Med       Date:  1960-07       Impact factor: 4.965

6.  Studies on uricase. I. Preparation, purification, and properties of a cuproprotein.

Authors:  H R MAHLER; G HUBSCHER; R BAUM
Journal:  J Biol Chem       Date:  1955-10       Impact factor: 5.157

7.  Tissue fractionation studies. 6. Intracellular distribution patterns of enzymes in rat-liver tissue.

Authors:  C DE DUVE; B C PRESSMAN; R GIANETTO; R WATTIAUX; F APPELMANS
Journal:  Biochem J       Date:  1955-08       Impact factor: 3.857

8.  Quantitative morphological studies on the livers and liver homogenates of rats fed 2-methyl- or 3 -methyl-4-dimethylaminoazobenzene.

Authors:  M J STRIEBICH; E SHELTON; W C SCHNEIDER
Journal:  Cancer Res       Date:  1953-03       Impact factor: 12.701

9.  Localization of acid phosphatase activity in hepatic lysosomes by means of electron microscopy.

Authors:  E ESSNER; A B NOVIKOFF
Journal:  J Biophys Biochem Cytol       Date:  1961-04

10.  Staining of tissue sections for electron microscopy with heavy metals. II. Application of solutions containing lead and barium.

Authors:  M L WATSON
Journal:  J Biophys Biochem Cytol       Date:  1958-11-25
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  68 in total

Review 1.  Zellweger syndrome and associated phenotypes.

Authors:  D R FitzPatrick
Journal:  J Med Genet       Date:  1996-10       Impact factor: 6.318

2.  Characterization of glyoxysomes from castor bean endosperm.

Authors:  R W Breidenbach; A Kahn; H Beevers
Journal:  Plant Physiol       Date:  1968-05       Impact factor: 8.340

3.  Isolation and Characterization of Microbodies from the Alga Chlorogonium elongatum.

Authors:  H Stabenau; H Beevers
Journal:  Plant Physiol       Date:  1974-06       Impact factor: 8.340

Review 4.  Peroxisomes: 40 years of histochemical staining, personal reminiscences.

Authors:  H Dariush Fahimi
Journal:  Histochem Cell Biol       Date:  2009-02-14       Impact factor: 4.304

5.  Cytochemical discrimination between catalases and peroxidases using diaminobenzidine.

Authors:  F Roels; E Wisse; B De Prest; J van der Meulen
Journal:  Histochemistry       Date:  1975

6.  Lysosome and phagosome stability in lethal cell injury. Morphologic tracer studies in cell injury due to inhibition of energy metabolism, immune cytolysis and photosensitization.

Authors:  H K Hawkins; J L Ericsson; P Biberfeld; B F Trump
Journal:  Am J Pathol       Date:  1972-08       Impact factor: 4.307

7.  Effects of catalase inhibitors on the ultrastructure and peroxidase activity of proliferating microbodies.

Authors:  P G Legg; R L Wood
Journal:  Histochemie       Date:  1970

8.  Ultrastructural features of in vitro propagated rat liver cells.

Authors:  P Biberfeld; J L Ericsson; P Perlmann; M Raftell
Journal:  Z Zellforsch Mikrosk Anat       Date:  1966

9.  A new method for the preparation of rat liver lysosomes. Separation of cell organelles of rat liver by carrier-free continuous electrophoresis.

Authors:  R Stahn; K P Maier; K Hannig
Journal:  J Cell Biol       Date:  1970-09       Impact factor: 10.539

10.  Amino acid oxidase of leukocytes in relation to H 2 O 2 -mediated bacterial killing.

Authors:  M R Eckstein; R L Baehner; D G Nathan
Journal:  J Clin Invest       Date:  1971-09       Impact factor: 14.808

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