Literature DB >> 4371898

Vascular reactivity in spontaneously hypertensive normotensive and hypotensive rats.

J Dupont, J Sassard.   

Abstract

1 Three strains of rats spontaneously hypertensive (HRS), normotensive (NS) and hypotensive (HOS), were selected by repeated inbreeding.2 In order to explain the different blood pressure levels observed, we have studied their vascular reactivity to noradrenaline and angiotensin II. Experiments were performed in anaesthetized ganglion-blocked, vagotomized rats.3 The reactivity to noradrenaline was significantly higher in HRS than in NS and HOS rats.4 The reactivity to angiotensin II appeared identical in the three strains used.

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Year:  1974        PMID: 4371898      PMCID: PMC1776642          DOI: 10.1111/j.1476-5381.1974.tb08560.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  13 in total

1.  A comparative study of the cardiovascular reactivity in various hypertensive and in normotensive rats.

Authors:  G Scholtysik; R Unda
Journal:  Arzneimittelforschung       Date:  1971-06

2.  Changes in sensitivity to angiotensin and renin. Studies on normal, nephrectomized, ureterligated, hypoxic, partially corticectomized or medullectomized and renal or spontaneously hypertensive rats.

Authors:  J Bing
Journal:  Acta Pathol Microbiol Scand       Date:  1969

3.  Vascular responses in mesenteric arteries from genetic and renal hypertensive rats.

Authors:  D D McGregor; F H Smirk
Journal:  Am J Physiol       Date:  1968-06

4.  Pre- and postjunctional supersensitivity of the mesenteric artery preparation from normotensive and hypertensive rats.

Authors:  G Haeusler; W Haefely
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1970

5.  Cardiovascular reactivity in rats with spontaneous inherited hypertension and constricted renal artery hypertension.

Authors:  E L Phelan
Journal:  Am Heart J       Date:  1966-01       Impact factor: 4.749

6.  Increased plasma renin activity in the spontaneously hypertensive rat.

Authors:  W De Jong; W Lovenberg; A Sjoerdsma
Journal:  Proc Soc Exp Biol Med       Date:  1972-04

7.  Structurally based increase of flow resistance in spontaneously hypertensive rats.

Authors:  B Folkow; M Hallbäck; Y Lundgren; L Weiss
Journal:  Acta Physiol Scand       Date:  1970-07

8.  Reactivity to norepinephrine and nature of the alpha adrenergic receptor in vascular smooth muscle of a genetically hypertensive rat.

Authors:  B V Clineschmidt; R G Geller; W C Govier; A Sjoerdsma
Journal:  Eur J Pharmacol       Date:  1970-04       Impact factor: 4.432

9.  Reactivity to noradrenaline of aortic strips and portal veins from spontaneously hypertensive and normotensive rats.

Authors:  M Hallbäck; Y Lundgren; L Weiss
Journal:  Acta Physiol Scand       Date:  1971-02

10.  Cytokinin of wheat germ transfer RNA: 6-(4-hydroxy-3-methyl-2-butenylamino)-2-methylthio-9-beta-D-ribofuranosylpurine.

Authors:  S M Hecht; N J Leonard; W J Burrows; D J Armstrong; F Skoog; J Occolowitz
Journal:  Science       Date:  1969-12-05       Impact factor: 47.728

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  3 in total

1.  Effect of parathyroidectomy on cardiovascular reactivity in rats with mineralocorticoid-induced hypertension.

Authors:  A Berthelot; A Gairard
Journal:  Br J Pharmacol       Date:  1978-02       Impact factor: 8.739

2.  Vascular reactivity of perfused vascular bed in spontaneously hypertensive and normotensive rats.

Authors:  B K Bhattacharya; N K Dadkar; A N Dohadwalla
Journal:  Br J Pharmacol       Date:  1977-02       Impact factor: 8.739

3.  Relation between calcium and cardiovascular reactivity in mineralocorticoid-induced hypertension in the rat.

Authors:  A Berthelot; A Gairard; M Goyault; F Pernot
Journal:  Br J Pharmacol       Date:  1980-10       Impact factor: 8.739

  3 in total

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