Literature DB >> 353811

Genetic analysis of the human cell surface: antigenic marker for the human X chromosome in human-mouse hybrids.

B P Dorman, N Shimizu, F H Ruddle.   

Abstract

Somatic cell hybrids of human fibroblasts and mouse A9 cells, carrying only a portion of the human X chromosome in a mouse chromosome background, were injected into C3H mice. The resulting mouse anti-hybrid cell antisera contain antibodies found to be human specific and to react with only those hybrid cells carrying the human X chromosome, as confirmed by essentially perfect concordance between antibody binding assayed by indirect immunofluorescence and presence of the human X-linked enzyme hypoxanthine phosphoribosyl-transferase determined by autoradiographic assay of [3H] hypoxanthine utilization. Heterogeneous mixtures of hybrid cells may be analyzed into fluorescent (X plus) and nonfluorescent (X minus) subpopulations and fractionated viably by using a fluorescence-activated cell sorter.

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Year:  1978        PMID： 353811      PMCID： PMC392553          DOI： 10.1073/pnas.75.5.2363

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  37 in total

1.  SELECTION OF HYBRIDS FROM MATINGS OF FIBROBLASTS IN VITRO AND THEIR PRESUMED RECOMBINANTS.

Authors:  J W LITTLEFIELD
Journal:  Science       Date:  1964-08-14       Impact factor: 47.728

2.  THREE DEGREES OF GUANYLIC ACID--INOSINIC ACID PYROPHOSPHORYLASE DEFICIENCY IN MOUSE FIBROBLASTS.

Authors:  J W LITTLEFIELD
Journal:  Nature       Date:  1964-09-12       Impact factor: 49.962

3.  THE INOSINIC ACID PYROPHOSPHORYLASE ACTIVITY OF MOUSE FIBROBLASTS PARTIALLY RESISTANT TO 8-AZAGUANINE.

Authors:  J W LITTLEFIELD
Journal:  Proc Natl Acad Sci U S A       Date:  1963-09       Impact factor: 11.205

4.  STUDIES ON THYMIDINE KINASE IN CULTURED MOUSE FIBROBLASTS.

Authors:  J W LITTLEFIELD
Journal:  Biochim Biophys Acta       Date:  1965-01-11

5.  THE LIMITED IN VITRO LIFETIME OF HUMAN DIPLOID CELL STRAINS.

Authors:  L HAYFLICK
Journal:  Exp Cell Res       Date:  1965-03       Impact factor: 3.905

6.  Regional mapping of the X-linked gene for a human cell surface antigen, SA-X.

Authors:  D W Buck; S J Goss; W F Bodmer
Journal:  Birth Defects Orig Artic Ser       Date:  1976

7.  Localization of the human alpha-globin structural gene to chromosome 16 in somatic cell hybrids by molecular hybridization assay.

Authors:  A Deisseroth; A Nienhuis; P Turner; R Velez; W F Anderson; F Ruddle; J Lawrence; R Creagan; R Kucherlapati
Journal:  Cell       Date:  1977-09       Impact factor: 41.582

8.  A sequential staining technique for the chromosomal analysis of the interspecific mouse/hamster and mouse/human somatic cell hybrids.

Authors:  C A Kozak; J B Lawrence; F H Ruddle
Journal:  Exp Cell Res       Date:  1977-03-01       Impact factor: 3.905

9.  The status of the gene map of the human chromosomes.

Authors:  V A McKusick; F H Ruddle
Journal:  Science       Date:  1977-04-22       Impact factor: 47.728

10.  Clonal growth of mammalian cells in vitro; growth characteristics of colonies from single HeLa cells with and without a feeder layer.

Authors:  T T PUCK; P I MARCUS; S J CIECIURA
Journal:  J Exp Med       Date:  1956-02-01       Impact factor: 14.307
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  10 in total

1.  Chromosome-specific organization of human alpha satellite DNA.

Authors:  H F Willard
Journal:  Am J Hum Genet       Date:  1985-05       Impact factor: 11.025

2.  Carcinoembryonic antigen family: expression in a mouse L-cell transfectant and characterization of a partial cDNA in bacteriophage lambda gt11.

Authors:  M E Kamarck; J J Elting; J T Hart; S J Goebel; P M Rae; M A Nothdurft; J J Nedwin; T R Barnett
Journal:  Proc Natl Acad Sci U S A       Date:  1987-08       Impact factor: 11.205

3.  Isolation and characterization of a major tandem repeat family from the human X chromosome.

Authors:  H F Willard; K D Smith; J Sutherland
Journal:  Nucleic Acids Res       Date:  1983-04-11       Impact factor: 16.971

4.  Contiguous deletion of the X-linked adrenoleukodystrophy gene (ABCD1) and DXS1357E: a novel neonatal phenotype similar to peroxisomal biogenesis disorders.

Authors:  Deyanira Corzo; William Gibson; Kisha Johnson; Grant Mitchell; Guy LePage; Gerald F Cox; Robin Casey; Carolyn Zeiss; Heidi Tyson; Garry R Cutting; Gerald V Raymond; Kirby D Smith; Paul A Watkins; Ann B Moser; Hugo W Moser; Steven J Steinberg
Journal:  Am J Hum Genet       Date:  2002-04-29       Impact factor: 11.025

5.  Partial purification and characterization of DNA from the human X chromosome.

Authors:  B J Schmeckpeper; K D Smith; B P Dorman; F H Ruddle; C C Talbot
Journal:  Proc Natl Acad Sci U S A       Date:  1979-12       Impact factor: 11.205

6.  Human transferrin receptor: expression of the receptor is assigned to chromosome 3.

Authors:  C A Enns; H A Suomalainen; J E Gebhardt; J Schröder; H H Sussman
Journal:  Proc Natl Acad Sci U S A       Date:  1982-05       Impact factor: 11.205

7.  An immunocytochemical screening of human-mouse cell hybrid colonies expressing a specific human gene.

Authors:  Y Shimizu; N Shimizu
Journal:  Biochem Genet       Date:  1981-02       Impact factor: 1.890

8.  Chromosomal basis of X chromosome inactivation: identification of a multigene domain in Xp11.21-p11.22 that escapes X inactivation.

Authors:  A P Miller; H F Willard
Journal:  Proc Natl Acad Sci U S A       Date:  1998-07-21       Impact factor: 11.205

9.  Genetic and biochemical characterization of human lymphocyte cell surface antigens. The A-1A5 and A-3A4 determinants.

Authors:  P M Peters; M E Kamarck; M E Hemler; J L Strominger; F H Ruddle
Journal:  J Exp Med       Date:  1984-05-01       Impact factor: 14.307

10.  Histone modifications within the human X centromere region.

Authors:  Brankica Mravinac; Lori L Sullivan; Jason W Reeves; Christopher M Yan; Kristen S Kopf; Christine J Farr; Mary G Schueler; Beth A Sullivan
Journal:  PLoS One       Date:  2009-08-12       Impact factor: 3.240
  10 in total

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