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43 in total

1. Localization of amplified CAD genes on rearranged chromosomes of Chinese hamster cells.

Authors: L Ottaggio; C Agnese; S Bonatti; P Cavolina; A Di Leonardo; M Miele; A Abbondandolo
Journal: Cytotechnology Date: 1987-10 Impact factor: 2.058

2. Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase.

Authors: Jie Wang; Kimberly A Stieglitz; James P Cardia; Evan R Kantrowitz
Journal: Proc Natl Acad Sci U S A Date: 2005-06-10 Impact factor: 11.205

3. Design, synthesis, and bioactivity of novel inhibitors of E. coli aspartate transcarbamoylase.

Authors: Joby Eldo; Sabrina Heng; Evan R Kantrowitz
Journal: Bioorg Med Chem Lett Date: 2006-12-21 Impact factor: 2.823

4. Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD.

Authors: Alba Ruiz-Ramos; Nada Lallous; Araceli Grande-García; Santiago Ramón-Maiques
Journal: Acta Crystallogr Sect F Struct Biol Cryst Commun Date: 2013-11-29

5. DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.

Authors: Kedar Hastak; Rajib K Paul; Mukesh K Agarwal; Vijay S Thakur; A R M Ruhul Amin; Sudesh Agrawal; R Michael Sramkoski; James W Jacobberger; Mark W Jackson; George R Stark; Munna L Agarwal
Journal: Proc Natl Acad Sci U S A Date: 2008-04-23 Impact factor: 11.205

6. Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage.

Authors: T G Paulson; A Almasan; L L Brody; G M Wahl
Journal: Mol Cell Biol Date: 1998-05 Impact factor: 4.272

N-(phosphonacetyl)-L-aspartate, a potent transition state analog inhibitor of aspartate transcarbamylase, blocks proliferation of mammalian cells in culture.

1. Localization of amplified CAD genes on rearranged chromosomes of Chinese hamster cells.

2. Structural basis for ordered substrate binding and cooperativity in aspartate transcarbamoylase.

3. Design, synthesis, and bioactivity of novel inhibitors of E. coli aspartate transcarbamoylase.

4. Expression, purification, crystallization and preliminary X-ray diffraction analysis of the aspartate transcarbamoylase domain of human CAD.

5. DNA synthesis from unbalanced nucleotide pools causes limited DNA damage that triggers ATR-CHK1-dependent p53 activation.

6. Gene amplification in a p53-deficient cell line requires cell cycle progression under conditions that generate DNA breakage.

7. Evolution and stability of chromosomal DNA coamplified with the CAD gene.

8. Substitutions in the aspartate transcarbamoylase domain of hamster CAD disrupt oligomeric structure.

9. A novel mechanism for resistance to the antimetabolite N-phosphonoacetyl-L-aspartate by Helicobacter pylori.

10. Effects of ciprofloxacin on eucaryotic pyrimidine nucleotide biosynthesis and cell growth.