Literature DB >> 4369980

Electron microscope studies of the antileprosy drug B663 (clofazimine; Lamprenel).

A C McDougall.   

Abstract

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Year:  1974        PMID： 4369980

Source DB:  PubMed          Journal:  Int J Lepr Other Mycobact Dis        ISSN： 0148-916X


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  10 in total

1.  Clofazimine shortens the duration of the first-line treatment regimen for experimental chemotherapy of tuberculosis.

Authors:  Sandeep Tyagi; Nicole C Ammerman; Si-Yang Li; John Adamson; Paul J Converse; Rosemary V Swanson; Deepak V Almeida; Jacques H Grosset
Journal:  Proc Natl Acad Sci U S A       Date:  2015-01-05       Impact factor: 11.205

2.  Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.

Authors:  Rosemary V Swanson; Nicole C Ammerman; Bongani Ngcobo; John Adamson; Chivonne Moodley; Afton Dorasamy; Sashen Moodley; Zinhle Mgaga; Linda A Bester; Sanil D Singh; Deepak V Almeida; Jacques H Grosset
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

3.  Pharmacokinetics and pharmacodynamics of clofazimine in a mouse model of tuberculosis.

Authors:  Rosemary V Swanson; John Adamson; Chivonne Moodley; Bongani Ngcobo; Nicole C Ammerman; Afton Dorasamy; Sashen Moodley; Zinhle Mgaga; Asa Tapley; Linda A Bester; Sanil Singh; Jacques H Grosset; Deepak V Almeida
Journal:  Antimicrob Agents Chemother       Date:  2015-03-09       Impact factor: 5.191

4.  Macrophage-Mediated Clofazimine Sequestration Is Accompanied by a Shift in Host Energy Metabolism.

Authors:  Julie Trexel; Gi S Yoon; Rahul K Keswani; Cora McHugh; Larisa Yeomans; Victor Vitvitsky; Ruma Banerjee; Sudha Sud; Yihan Sun; Gus R Rosania; Kathleen A Stringer
Journal:  J Pharm Sci       Date:  2016-12-20       Impact factor: 3.534

5.  Chemical Analysis of Drug Biocrystals: A Role for Counterion Transport Pathways in Intracellular Drug Disposition.

Authors:  Rahul K Keswani; Jason Baik; Larisa Yeomans; Chuck Hitzman; Allison M Johnson; Ashtamurthy S Pawate; Paul J A Kenis; Nair Rodriguez-Hornedo; Kathleen A Stringer; Gus R Rosania
Journal:  Mol Pharm       Date:  2015-06-05       Impact factor: 4.939

6.  Molecular imaging of intracellular drug-membrane aggregate formation.

Authors:  Jason Baik; Gus R Rosania
Journal:  Mol Pharm       Date:  2011-08-12       Impact factor: 4.939

7.  Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas.

Authors:  Scott M Irwin; Veronica Gruppo; Elizabeth Brooks; Janet Gilliland; Michael Scherman; Matthew J Reichlen; Rachel Leistikow; Igor Kramnik; Eric L Nuermberger; Martin I Voskuil; Anne J Lenaerts
Journal:  Antimicrob Agents Chemother       Date:  2014-05-05       Impact factor: 5.191

8.  Identification of crystals of the rimino-phenazine compound B663 (Lamprene: clofazimine) in mouse spleen macrophages by thin layer chromatography and mass spectrum analysis.

Authors:  R T Aplin; A C McDougall
Journal:  Experientia       Date:  1975-04-15

9.  Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response.

Authors:  Jason Baik; Kathleen A Stringer; Gerta Mane; Gus R Rosania
Journal:  Antimicrob Agents Chemother       Date:  2012-12-21       Impact factor: 5.191

10.  Macrophages sequester clofazimine in an intracellular liquid crystal-like supramolecular organization.

Authors:  Jason Baik; Gus R Rosania
Journal:  PLoS One       Date:  2012-10-11       Impact factor: 3.240
  10 in total

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