Literature DB >> 1120525

Identification of crystals of the rimino-phenazine compound B663 (Lamprene: clofazimine) in mouse spleen macrophages by thin layer chromatography and mass spectrum analysis.

R T Aplin, A C McDougall.   

Abstract

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Year:  1975        PMID： 1120525     DOI： 10.1007/bf02026384

Source DB:  PubMed          Journal:  Experientia        ISSN： 0014-4754


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  14 in total

1.  The control of neuritis in leprosy with clofazimine.

Authors:  R E Pfaltzgraff
Journal:  Int J Lepr Other Mycobact Dis       Date:  1972 Oct-Dec

2.  Electron microscope studies of the antileprosy drug B663 (clofazimine; Lamprenel).

Authors:  A C McDougall
Journal:  Int J Lepr Other Mycobact Dis       Date:  1974 Jan-Mar

3.  Treatment of moderately severe erythema nodosum leprosum with clofazimine--a controlled trial.

Authors:  H S Helmy; J M Pearson; M F Waters
Journal:  Lepr Rev       Date:  1971-09       Impact factor: 0.537

4.  Forty-four months' experience in the treatment of leprosy with clofazimine (Lamprene (Geigy)).

Authors:  E J Schulz
Journal:  Lepr Rev       Date:  1971-09       Impact factor: 0.537

5.  Controlled drug trial of B.663 compared with DDS. Preliminary (48 week) report.

Authors:  J G Tolentino; J N Rodriquez; R M Abalos
Journal:  Int J Lepr Other Mycobact Dis       Date:  1971 Jul-Sep

6.  Evaluation of B.663 in human leprosy.

Authors:  A J Atkinson; J N Sheagren; J B Rubio; V Knight
Journal:  Int J Lepr Other Mycobact Dis       Date:  1967 Apr-Jun

7.  A study of skin pigmentation by clofazimine.

Authors:  L Levy; H P Randall
Journal:  Int J Lepr Other Mycobact Dis       Date:  1970 Oct-Dec

8.  Efficacy of clofazimine in the prophylaxis and suppression of reactive phases of lepromatous leprosy.

Authors:  A B Karat; A Jeevaratnam; S Karat; P S Rao
Journal:  Int J Lepr Other Mycobact Dis       Date:  1971 Oct-Dec

9.  Bacteriological effect of Lamprene (clofazimine) in lepromatous leprosy (report of one year's treatment of 44 patients with 100 mg of Lamprene daily).

Authors:  D L Leiker; W Blenska; D Carling; M Fitzherbert; P Larssen
Journal:  Lepr Rev       Date:  1971-06       Impact factor: 0.537

10.  The antileprosy agent B.663 (Clofazimine) and the reticuloendothelial system.

Authors:  M L Conalty; V C Barry; A Jina
Journal:  Int J Lepr Other Mycobact Dis       Date:  1971 Apr-Jun
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  7 in total

1.  Elasticity in Macrophage-Synthesized Biocrystals.

Authors:  Elizabeth M Horstman; Rahul K Keswani; Benjamin A Frey; Phillip M Rzeczycki; Vernon LaLone; Jeffery A Bertke; Paul J A Kenis; Gus R Rosania
Journal:  Angew Chem Int Ed Engl       Date:  2017-01-12       Impact factor: 15.336

2.  Clofazimine Contributes Sustained Antimicrobial Activity after Treatment Cessation in a Mouse Model of Tuberculosis Chemotherapy.

Authors:  Rosemary V Swanson; Nicole C Ammerman; Bongani Ngcobo; John Adamson; Chivonne Moodley; Afton Dorasamy; Sashen Moodley; Zinhle Mgaga; Linda A Bester; Sanil D Singh; Deepak V Almeida; Jacques H Grosset
Journal:  Antimicrob Agents Chemother       Date:  2016-04-22       Impact factor: 5.191

3.  Chemical Analysis of Drug Biocrystals: A Role for Counterion Transport Pathways in Intracellular Drug Disposition.

Authors:  Rahul K Keswani; Jason Baik; Larisa Yeomans; Chuck Hitzman; Allison M Johnson; Ashtamurthy S Pawate; Paul J A Kenis; Nair Rodriguez-Hornedo; Kathleen A Stringer; Gus R Rosania
Journal:  Mol Pharm       Date:  2015-06-05       Impact factor: 4.939

4.  Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas.

Authors:  Scott M Irwin; Veronica Gruppo; Elizabeth Brooks; Janet Gilliland; Michael Scherman; Matthew J Reichlen; Rachel Leistikow; Igor Kramnik; Eric L Nuermberger; Martin I Voskuil; Anne J Lenaerts
Journal:  Antimicrob Agents Chemother       Date:  2014-05-05       Impact factor: 5.191

5.  Clofazimine analogs with efficacy against experimental tuberculosis and reduced potential for accumulation.

Authors:  Yu Lu; Meiqin Zheng; Bin Wang; Lei Fu; Weijie Zhao; Peng Li; Jian Xu; Hui Zhu; Haixia Jin; Dali Yin; Haihong Huang; Anna M Upton; Zhenkun Ma
Journal:  Antimicrob Agents Chemother       Date:  2011-08-15       Impact factor: 5.191

6.  Multiscale distribution and bioaccumulation analysis of clofazimine reveals a massive immune system-mediated xenobiotic sequestration response.

Authors:  Jason Baik; Kathleen A Stringer; Gerta Mane; Gus R Rosania
Journal:  Antimicrob Agents Chemother       Date:  2012-12-21       Impact factor: 5.191

7.  Macrophages sequester clofazimine in an intracellular liquid crystal-like supramolecular organization.

Authors:  Jason Baik; Gus R Rosania
Journal:  PLoS One       Date:  2012-10-11       Impact factor: 3.240
  7 in total

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