Literature DB >> 4365376

NAD(P) glycohydrolase deficiency in human erythrocytes and alteration of cytosol NADH-methemoglobin diaphorase by membrane NAD-glycohydrolase activity.

H Frischer, R Nelson, C Noyes, P E Carson, J E Bowman, K H Rieckmann, F Ajmar.   

Abstract

Erythrocytic NADH methemoglobin diaphorase acquires NADH-dichlorophenolindophenol diaphorase activity when enzyme-associated NAD is removed. This transformation is reversible and can be mediated by membrane NAD glycohydrolase (EC 3.2.2.5) in hemolysates as well as in intact cells exposed to hydrogen peroxide. It is abolished either in NADH methemoglobin diaphorase deficiency or in NAD(P) glycohydrolase (EC 3.2.2.6) deficiency which is common in Afro-American but not in European-American adults. Activities of erythrocytic NADP glycohydrolase and NAD glycohydrolase appear to depend on a single membrane enzyme.

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Year:  1973        PMID： 4365376      PMCID： PMC433745          DOI： 10.1073/pnas.70.8.2406

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  12 in total

1.  [Distribution of DPN- and TPN-specific nucleosidases in erythrocytes of various animal species].

Authors:  E HOFMANN; F NOLL
Journal:  Acta Biol Med Ger       Date:  1961

2.  Further studies on the properties and assay of glucose 6-phosphate dehydrogenase and 6-phosphogluconate dehydrogenase of rat liver.

Authors:  G E GLOCK; P McLEAN
Journal:  Biochem J       Date:  1953-10       Impact factor: 3.857

3.  Heterogeneity of the enzymatic defect in congenital methemoglobinemia.

Authors:  G E Bloom; H S Zarkowsky
Journal:  N Engl J Med       Date:  1969-10-23       Impact factor: 91.245

4.  Interrelation of stromal NAD(P)ase and human erythrocytic 6-phosphogluconic dehydrogenase.

Authors:  F Ajmar; B Scharrer; F Hashimoto; P E Carson
Journal:  Proc Natl Acad Sci U S A       Date:  1968-02       Impact factor: 11.205

5.  Deficiency of erythrocyte nicotinamide adenine dinucleotide nucleosidase (NADase) activity in the Negro.

Authors:  W G Ng; G N Donnell; W Bergren
Journal:  Nature       Date:  1968-01-06       Impact factor: 49.962

6.  Erythrocytic glutathione reductase, glucose-6-phosphate dehydrogenase, and 6-phosphogluconic dehydrogenase deficiencies in populations of the United States, South Vietnam, Iran, and Ethiopia.

Authors:  H Frischer; J E Bowman; P E Carson; K H Rieckmann; D Willerson; E J Colwell
Journal:  J Lab Clin Med       Date:  1973-04

7.  New method for determining ferrihemoglobin reductase (NADH-methemoglobin reductase) in erythrocytes.

Authors:  E Hegesh; N Calmanovici; M Avron
Journal:  J Lab Clin Med       Date:  1968-08

8.  NADH diaphorase: an inherited variant associated with normal methemoglobin reduction.

Authors:  J C Detter; J E Anderson; E R Giblett
Journal:  Am J Hum Genet       Date:  1970-01       Impact factor: 11.025

9.  Visual test for erythrocytic glucose-6-phosphate dehydrogenase, 6-phosphogluconic dehydrogenase, and glutathione reductase deficiencies.

Authors:  H Frischer; P E Carson; J E Bowman; K H Rieckmann
Journal:  J Lab Clin Med       Date:  1973-04

10.  A starch-gel electrophoretic method for the study of diaphorase isozymes and preliminary results with sheep and human erythrocytes.

Authors:  G J Brewer; J W Eaton; C S Knutsen; C C Beck
Journal:  Biochem Biophys Res Commun       Date:  1967-10-26       Impact factor: 3.575
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  1 in total

1.  Electrophoretic demonstration and inital characterization of human red cell NAD(P)+ase.

Authors:  R Ravazzolo; G Bruzzone; C Garrè; F Ajmar
Journal:  Biochem Genet       Date:  1976-10       Impact factor: 1.890
  1 in total

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