Literature DB >> 4361242

A depression of cell-mediated immunity to measles antigen in patients with systemic lupus erythematosus.

V Utermohlen, J B Winfield, J B Zabriskie, H G Kunkel.   

Abstract

Using the direct migration inhibition test, response to measles antigen in patients with systemic lupus erythematosus (SLE) was found to be decreased when compared with that of normal subjects. No alteration was observed in similar experiments using parainfluenza type 1 and rubella antigens. The specific decrease in measles antigen effect showed no obvious correlation with activity of SLE or with the presence of lymphocytotoxic antibodies. Whether the specificity of the decrease in reactivity is due to some particular relationship between the measles virus or antigen and SLE, or to the possibility that measles reactivity is a more sensitive indicator of a generalized defect of cell-mediated immunity, remains unclear.

Entities:  

Mesh：

Substances：

Year:  1974        PMID： 4361242      PMCID： PMC2139577          DOI： 10.1084/jem.139.4.1019

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  11 in total

1.  Myxovirus antibody increases in human connective tissue disease.

Authors:  P E Phillips; C L Christian
Journal:  Science       Date:  1970-05-22       Impact factor: 47.728

2.  Virus-like structure in multiple sclerosis.

Authors:  I Watanabe; H Okazaki
Journal:  Lancet       Date:  1973-09-08       Impact factor: 79.321

3.  Abnormal structures in circulating lymphocytes from patients with systemic lupus erythematosus and related diseases.

Authors:  P M Grrimley; J L Decker; H J Michelitch; M M Frantz
Journal:  Arthritis Rheum       Date:  1973 May-Jun

4.  Antibodies to viral antigens in systemic lupus erythematosus.

Authors:  F B Hollinger; J T Sharp; M D Lidsky; W E Rawls
Journal:  Arthritis Rheum       Date:  1971 Jan-Feb

5.  Impaired mixed leucocyte reaction in some different diseases, notably multiple sclerosis and various arthritides.

Authors:  H Hedberg; B Källén; B Löw; O Nilsson
Journal:  Clin Exp Immunol       Date:  1971-08       Impact factor: 4.330

6.  Virus-like structures in lupus erythematosus.

Authors:  K Kawano; L Miller; P Kimmelstiel
Journal:  N Engl J Med       Date:  1969-11-27       Impact factor: 91.245

7.  Specific inhibition of the in vitro migration of leucocytes in ulcerative colitis and Crohn's disease.

Authors:  G Bendixen
Journal:  Scand J Gastroenterol       Date:  1967       Impact factor: 2.423

8.  Idiotypic determinants of immunoglobulin M detected on the surface of human lymphocytes by cytotoxicity assays.

Authors:  P Wernet; T Feizi; H G Kunkel
Journal:  J Exp Med       Date:  1972-09-01       Impact factor: 14.307

9.  Antibodies to a specific surface antigen of T cells in human sera inhibiting mixed leukocyte culture reactions.

Authors:  P Wernet; H G Kunkel
Journal:  J Exp Med       Date:  1973-10-01       Impact factor: 14.307

10.  Virus antibody levels in systemic lupus erythematosus.

Authors:  E R Hurd; W Dowdle; H Casey; M Ziff
Journal:  Arthritis Rheum       Date:  1972 May-Jun
View more
  5 in total

1.  Mixed lymphocyte culture determinants and C2 deficiency: LD-7a associated with C2 deficiency in four families.

Authors:  S M Fu; R Stern; H G Kunkel; B Dupont; J A Hansen; N K Day; R A Good; C Jersild; M Fotino
Journal:  J Exp Med       Date:  1975-08-01       Impact factor: 14.307

2.  A 'profile' of immune responsiveness in multiple sclerosis.

Authors:  G R Symington; I R Mackay; S Whittingham; J White; J D Buckley
Journal:  Clin Exp Immunol       Date:  1978-02       Impact factor: 4.330

3.  Relationship of phytohaemagglutinin-induced lymphocyte transformation to disease activity in systemic lupus erythematosus.

Authors:  P Hughes; S Holt; N R Rowell; J K Dodd
Journal:  Ann Rheum Dis       Date:  1976-04       Impact factor: 19.103

4.  Immune function in systemic lupus erythematosus. Impairment of in vitro T-cell proliferation and in vivo antibody response to exogenous antigen.

Authors:  A B Gottlieb; R G Lahita; N Chiorazzi; H G Kunkel
Journal:  J Clin Invest       Date:  1979-05       Impact factor: 14.808

5.  Henry G. Kunkel 1916-1983. An appreciation of the man and his scientific contributions & a bibliography of his research papers.

Authors:  A G Bearn; F J Dixon; B Benacerraf
Journal:  J Exp Med       Date:  1985-05-01       Impact factor: 14.307
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.