Literature DB >> 4361099

Dexamethasone stimulation of murine mammary tumor virus expression: a tissue culture source of virus.

W P Parks, E M Scolnick, E H Kozikowski.   

Abstract

In mouse cell lines derived from mammary adenocarcinomnas, the synthetic steroid dexamnethasone stimulates production of murine mammary tumor virus. Viral RNA and antigens are increased as much as 20-fold, and culture fluid supernatants from steroid-treated cells contain type B particles with reverse transcriptase. These cells provide a possible tissue culture source of this virus and a model system for studying the mechanism of action of corticosteroids and the regulation of transcription of integrated viral DNA.

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Year:  1974        PMID： 4361099     DOI： 10.1126/science.184.4133.158

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  46 in total

Review 1.  Factors controlling the expression of mouse mammary tumour virus.

Authors:  W H Günzburg; B Salmons
Journal:  Biochem J       Date:  1992-05-01       Impact factor: 3.857

2.  Murine mammary tumor virus: characterization of infection of nonmurine cells.

Authors:  A B Vaidya; E Y Lasfargues; G Heubel; J C Lasfargues; D H Moore
Journal:  J Virol       Date:  1976-06       Impact factor: 5.103

3.  Effect of chemical inactivating agents on glucocorticoid receptor proteins in mouse and hamster cells.

Authors:  H A Young; W P Parks; E M Scolnick
Journal:  Proc Natl Acad Sci U S A       Date:  1975-08       Impact factor: 11.205

4.  Glucocorticoids induce focus formation and increase sarcoma viral expression in a mink cell line that contains a murine sarcoma viral genome.

Authors:  D R Lowy; E M Scolnick
Journal:  J Virol       Date:  1978-01       Impact factor: 5.103

5.  Mapping of linear and circular forms of mouse mammary tumor virus DNA with restriction endonucleases: evidence for a large specific deletion occurring at high frequency during circularization.

Authors:  P R Shank; J C Cohen; H E Varmus; K R Yamamoto; G M Ringold
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

6.  A human breast tumor cell line (BT-474) that supports mouse mammary tumor virus replication.

Authors:  E Y Lasfargues; W G Coutinho; A S Dion
Journal:  In Vitro       Date:  1979-09

7.  Viral gene expression in murine sarcoma virus(murine leukemia virus)-infected cells.

Authors:  D Dina; E E Penhoet
Journal:  J Virol       Date:  1978-09       Impact factor: 5.103

8.  Integration and transcription of mouse mammary tumor virus DNA in rat hepatoma cells.

Authors:  G M Ringold; P R Shank; H E Varmus; J Ring; K R Yamamoto
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

9.  Modulation of mouse mammary tumor virus production in the MJY-alpha cell line.

Authors:  M J Yagi; P B Blair; M A Lane
Journal:  J Virol       Date:  1978-11       Impact factor: 5.103

10.  Increased concentration of an indigenous proviral mouse mammary tumor virus long terminal repeat-containing transcript is associated with neoplastic transformation of mammary epithelium in C3H/Sm mice.

Authors:  D E Graham; D Medina; G H Smith
Journal:  J Virol       Date:  1984-03       Impact factor: 5.103
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