Literature DB >> 435518

An oligosaccharide component in proteoglycans of articular cartilage.

E J Thonar, M B Sweet.   

Abstract

Two types of sialic acid-containing component are released from articular cartilage proteoglycan monomer (D1) treated with 0.05 M NaOH containing 1 M NaBH4. The smaller component, which has not been described before, contains galactosamine, glucosamine, galactose and sialic acid (Molar ratio 1:1:1:2). It is eluted from ECTEOLA-cellulose with low molarity (0.4 M) sodium formate and has Kav of 0.70 on Bio-gel P30. Its presence on the proteoglycan monomer was demonstrated at all stages of foetal and adult life.

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Year:  1979        PMID： 435518     DOI： 10.1016/0304-4165(79)90281-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  8 in total

1.  Degradation of proteoglycan aggregate by a cartilage metalloproteinase. Evidence for the involvement of stromelysin in the generation of link protein heterogeneity in situ.

Authors:  Q Nguyen; G Murphy; P J Roughley; J S Mort
Journal:  Biochem J       Date:  1989-04-01       Impact factor: 3.857

2.  The identification and characterization of two populations of aggregating proteoglycans of high buoyant density isolated from post-natal human articular cartilages of different ages.

Authors:  C Webber; T T Glant; P J Roughley; A R Poole
Journal:  Biochem J       Date:  1987-12-15       Impact factor: 3.857

3.  Cell-free translation of messenger RNA for chondroitin sulphate proteoglycan core protein in rat cartilage.

Authors:  B M Vertel; W B Upholt; A Dorfman
Journal:  Biochem J       Date:  1984-01-01       Impact factor: 3.857

4.  Differences in the rates of aggregation of proteoglycans from human articular cartilage and chondrosarcoma.

Authors:  M T Bayliss; G D Ridgway; S Y Ali
Journal:  Biochem J       Date:  1983-12-01       Impact factor: 3.857

5.  Age-related changes in the chemical composition of bovine articular cartilage. The structure of high-density proteoglycans.

Authors:  H G Garg; D A Swann
Journal:  Biochem J       Date:  1981-02-01       Impact factor: 3.857

6.  The inability to prepare high-buoyant-density proteoglycan aggregates from extracts of normal adult human articular cartilage.

Authors:  P J Roughley; R J White; A R Poole; J S Mort
Journal:  Biochem J       Date:  1984-08-01       Impact factor: 3.857

7.  The presence of a cartilage-like proteoglycan in the adult human meniscus.

Authors:  P J Roughley; D McNicol; V Santer; J Buckwalter
Journal:  Biochem J       Date:  1981-07-01       Impact factor: 3.857

8.  Synthesis of cartilage matrix by mammalian chondrocytes in vitro. II. Maintenance of collagen and proteoglycan phenotype.

Authors:  K E Kuettner; V A Memoli; B U Pauli; N C Wrobel; E J Thonar; J C Daniel
Journal:  J Cell Biol       Date:  1982-06       Impact factor: 10.539
  8 in total

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