Literature DB >> 4346628

Mutagenesis and enrichment of auxotrophs in Penicillium chrysogenum.

P S Masurekar, M P Kahgan, A L Demain.   

Abstract

An efficient method for isolation of auxotrophs of Penicillium chyrysogenum involving mutagenesis with ethyl methanesulfonate followed by enrichment with sodium pentachlorophenate was developed. The auxotroph frequencies obtained were 30 to 40%.

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Year:  1972        PMID： 4346628      PMCID： PMC380710          DOI： 10.1128/am.24.6.995-996.1972

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  3 in total

1.  An enrichme technique for isolation of auxotrophic mutants of microorganisms using sodium pentachlorophenate.

Authors:  P L Ganju; M R Iyengar
Journal:  Hindustan Antibiot Bull       Date:  1968-08

2.  Lysine control of penicillin biosynthesis.

Authors:  P S Masurekar; A L Demain
Journal:  Can J Microbiol       Date:  1972-07       Impact factor: 2.419

3.  Mutangenesis by N-methyl-N'-nitro-N-nitrosoguanidine (NTG) in Streptomyces coelicolor.

Authors:  V Delić; D A Hopwood; E J Friend
Journal:  Mutat Res       Date:  1970-02       Impact factor: 2.433
  3 in total
  1 in total

1.  Impaired penicillin production in lysine regulatory mutants of Penicillium chrysogenum.

Authors:  P S Masurekar; A L Demain
Journal:  Antimicrob Agents Chemother       Date:  1974-09       Impact factor: 5.191
  1 in total

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