Literature DB >> 15830488

Impaired penicillin production in lysine regulatory mutants of Penicillium chrysogenum.

P S Masurekar, A L Demain.   

Abstract

Lysine-regulatory mutants of Penicillium chrysogenum which excrete lysine were found to be deficient in production of penicillin. A revertant recovered the ability to produce penicillin.

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Year:  1974        PMID： 15830488      PMCID： PMC444652          DOI： 10.1128/AAC.6.3.366

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  6 in total

1.  Inhibition of penicillin formation by lysine.

Authors:  A L DEMAIN
Journal:  Arch Biochem Biophys       Date:  1957-03       Impact factor: 4.013

2.  Inhibition of penicillin formation by amino acid analogs.

Authors:  A L DEMAIN
Journal:  Arch Biochem Biophys       Date:  1956-09       Impact factor: 4.013

3.  Improvement of kasugamycin-producing strain by the agar piece method and the prototroph method.

Authors:  T Ichikawa; M Date; T Ishikura; A Ozaki
Journal:  Folia Microbiol (Praha)       Date:  1971       Impact factor: 2.099

4.  Lysine control of penicillin biosynthesis.

Authors:  P S Masurekar; A L Demain
Journal:  Can J Microbiol       Date:  1972-07       Impact factor: 2.419

5.  Studies on candicidin biogenesis.

Authors:  C M Liu; L E McDaniel; C P Schaffner
Journal:  J Antibiot (Tokyo)       Date:  1972-02       Impact factor: 2.649

6.  Mutagenesis and enrichment of auxotrophs in Penicillium chrysogenum.

Authors:  P S Masurekar; M P Kahgan; A L Demain
Journal:  Appl Microbiol       Date:  1972-12
  6 in total
  4 in total

Review 1.  Genetics of antibiotic production.

Authors:  D A Hopwood; M J Merrick
Journal:  Bacteriol Rev       Date:  1977-09

2.  Catabolism of lysine in Penicillium chrysogenum leads to formation of 2-aminoadipic acid, a precursor of penicillin biosynthesis.

Authors:  C Esmahan; E Alvarez; E Montenegro; J F Martin
Journal:  Appl Environ Microbiol       Date:  1994-06       Impact factor: 4.792

3.  Effects of lysine analogs on Penicillium chrysogenum.

Authors:  C G Friedrich; A L Demain
Journal:  Appl Environ Microbiol       Date:  1977-12       Impact factor: 4.792

4.  Enhancement of bacitracin biosynthesis by branched-chain amino acids in a regulatory mutant of Bacillus licheniformis.

Authors:  V Supek; S Gamulin; V Delić
Journal:  Folia Microbiol (Praha)       Date:  1985       Impact factor: 2.099
  4 in total

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