| Literature DB >> 4346281 |
G Khoury, J C Byrne, K K Takemoto, M A Martin.
Abstract
The pattern of simian virus 40 (SV40) deoxyribonucleic acid transcription has been examined in 11 SV40-transformed cell lines. In all cases, substantial regions of the minus strand (35-75%) appeared to be transcribed. In the lines tested, these regions included the "early" gene sequences. The SV40-specific ribonucleic acid from at least two of the transformed cell lines represented significantly greater portions of the minus strand than are represented in "early" lytic ribonucleic acid. Small regions of the plus strand appeared to be transcribed in only two of the transformed cell lines.Entities:
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Year: 1973 PMID: 4346281 PMCID: PMC355060
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103