| Literature DB >> 4333982 |
G Miller, T Shope, H Lisco, D Stitt, M Lipman.
Abstract
Blood leukocytes of two species of new world primates, other than human, transform following exposure to Epstein-Barr virus. The transformed simian cells produce Epstein-Barr virus antigens and infectious (transforming) virus. The simian lymphoblastoid cells form multinucleate giant cells that appear to be selective sites for the production of Epstein-Barr virus. Multinucleate cells reveal intranuclear inclusions; in both species, a large proportion of giant cells contain Epstein-Barr virus antigen detectable by immunofluorescence.Entities:
Mesh:
Substances:
Year: 1972 PMID: 4333982 PMCID: PMC426463 DOI: 10.1073/pnas.69.2.383
Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN: 0027-8424 Impact factor: 11.205