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Literature DB >> 4321268

Homologies in amino acid composition and structure of histone F2al isolated from human leukaemic cells.

Abstract

Histones F2al extracted from normal and neoplastic cells possess similar amino acid compositions. Tryptic and chymotryptic peptides of the F2al histones have identical chromato-electrophoretic R(F) values. It is concluded that histones F2al from various sources have similar overall structures. The observed differences in the ratios of in-N-monomethyl- and di-in-N-methyl-lysine in the histones from normal and neoplastic cells may be of significance with respect to gene regulation.

Entities: Chemical Species

Mesh：

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Year: 1970 PMID： 4321268 PMCID： PMC1179338 DOI： 10.1042/bj1190165

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

25 in total

1. Structural analysis of the glycine-rich, arginine-rich histone. I. Sequence of the carbosyl-terminal portion.

Authors: P Sautiere; W C Starbuck; C Roth; H Busch
Journal: J Biol Chem Date: 1968-11-25 Impact factor: 5.157

2. N-Terminal acetyl-peptides from two calf thymus histones.

Authors: D M Phillips
Journal: Biochem J Date: 1968-03 Impact factor: 3.857

3. Chemical studies of histone acetylation. The occurrence of epsilon-N-acetyllysine in the f2a1 histone.

Authors: E L Gershey; G Vidali; V G Allfrey
Journal: J Biol Chem Date: 1968-10-10 Impact factor: 5.157

4. Sequence homology and role of cysteine in plant and animal arginine-rich histones.

Authors: D M Fambrough; J Bonner
Journal: J Biol Chem Date: 1968-09-10 Impact factor: 5.157

5. The carboxyl-terminal sequence of porcine pepsin.

Authors: T A Dopheide; S Moore; W H Stein
Journal: J Biol Chem Date: 1967-04-25 Impact factor: 5.157

6. Studies on histones. 7. Preparative methods for histone fractions from calf thymus.

Authors: E W Johns
Journal: Biochem J Date: 1964-07 Impact factor: 3.857

7. The heterogeneity of arginine-rich histones.

Authors: L S Hnilica; L G Bess
Journal: Anal Biochem Date: 1965-09 Impact factor: 3.365

8. A method for the selective extraction of histone fractions f2(a)1 and f2(a)2 from calf thymus deoxyribonucleoprotein at pH7.

Authors: E W Johns
Journal: Biochem J Date: 1967-11 Impact factor: 3.857

Homologies in amino acid composition and structure of histone F2al isolated from human leukaemic cells.

1. Structural analysis of the glycine-rich, arginine-rich histone. I. Sequence of the carbosyl-terminal portion.

2. N-Terminal acetyl-peptides from two calf thymus histones.

3. Chemical studies of histone acetylation. The occurrence of epsilon-N-acetyllysine in the f2a1 histone.

4. Sequence homology and role of cysteine in plant and animal arginine-rich histones.

5. The carboxyl-terminal sequence of porcine pepsin.

6. Studies on histones. 7. Preparative methods for histone fractions from calf thymus.

7. The heterogeneity of arginine-rich histones.

8. A method for the selective extraction of histone fractions f2(a)1 and f2(a)2 from calf thymus deoxyribonucleoprotein at pH7.

9. The fractionation of arginine-rich histones from fetal calf thymus by exclusion chromatography.

10. On the similarity of plant and animal histones.

1. Human leukemic cells: cytochemical studies on nuclear proteins.

2. In vivo and in vitro methylation of lysine residues of Euglena gracilis histone H1.

3. Human leukaemic cells. Determination of trace elements in nucleic acids and histones by neutron-activation analyses.