Literature DB >> 4317924

Tilorone hydrochloride: mode of action.

G D Mayer, R F Krueger.   

Abstract

An antiviral serum component is found in mice treated orally with tilorone hydrochloride. The active material fulfills sufficient biological criteria to be classified as an interferon.

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Substances：

Year:  1970        PMID： 4317924     DOI： 10.1126/science.169.3951.1214

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  37 in total

1.  Comparation interferon- inducing and antiviral properties of 2-amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), tilorone hydrochloride, and polyinosinic-polycytidylic acid.

Authors:  D A Stringfellow
Journal:  Antimicrob Agents Chemother       Date:  1977-06       Impact factor: 5.191

2.  Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.

Authors:  Sean Ekins; Mary A Lingerfelt; Jason E Comer; Alexander N Freiberg; Jon C Mirsalis; Kathleen O'Loughlin; Anush Harutyunyan; Claire McFarlane; Carol E Green; Peter B Madrid
Journal:  Antimicrob Agents Chemother       Date:  2018-01-25       Impact factor: 5.191

3.  Radioprotective activity of interferon inducers.

Authors:  M Tálas; E Szolgay
Journal:  Arch Virol       Date:  1978       Impact factor: 2.574

4.  Stimulation of humoral immune response by tilorone hydrochloride.

Authors:  T Diamantstein
Journal:  Immunology       Date:  1973-04       Impact factor: 7.397

5.  Increased toxicity of double-stranded ribonucleic acid in virus-infected animals.

Authors:  E De Clercq; W E Stewart; P De Somer
Journal:  Infect Immun       Date:  1973-02       Impact factor: 3.441

6.  Tilorone hydrochloride: an oral interferon-inducing agent.

Authors:  D A Stringfellow; L A Glasgow
Journal:  Antimicrob Agents Chemother       Date:  1972-08       Impact factor: 5.191

7.  Tilorone hydrochloride: lack of correlation between interferon induction and viral protection.

Authors:  D J Giron; J P Schmidt; F F Pindak
Journal:  Antimicrob Agents Chemother       Date:  1972-01       Impact factor: 5.191

8.  Effect of tilorone on susceptibility of mice to primary or secondary infection with Listeria monocytogenes.

Authors:  R Gruenewald; S Levine
Journal:  Infect Immun       Date:  1976-06       Impact factor: 3.441

9.  alpha7 nicotinic acetylcholine receptor agonist properties of tilorone and related tricyclic analogues.

Authors:  C A Briggs; M R Schrimpf; D J Anderson; E J Gubbins; J H Grønlien; M Håkerud; H Ween; K Thorin-Hagene; J Malysz; J Li; W H Bunnelle; M Gopalakrishnan; M D Meyer
Journal:  Br J Pharmacol       Date:  2007-12-24       Impact factor: 8.739

10.  Evaluation of various analogues of tilorone hydrochloride against Venezuelan equine encephalitis virus in mice.

Authors:  R W Kuehne; W L Pannier; E L Stephen
Journal:  Antimicrob Agents Chemother       Date:  1977-01       Impact factor: 5.191
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