Literature DB >> 431717

Construction of a site-specific, deletion-frameshift mutation in an essential gene of bacteriophage phiX174.

M Z Humayun, R W Chambers.   

Abstract

By in vitro methods, we have deleted 80 nucleotides from a preselected site in the coding sequence of gene G of bacteriophage phiX174. This mutant (Gdelta/FS ZH1) also carries a--2 frameshift. The mutation is lethal, but mutant virus can be stably maintained on host strains bearing plasmids carrying phiX gene G.

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Year:  1979        PMID： 431717     DOI： 10.1038/278524a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  2 in total

1.  Sequence specificity in aflatoxin B1--DNA interactions.

Authors:  K F Muench; R P Misra; M Z Humayun
Journal:  Proc Natl Acad Sci U S A       Date:  1983-01       Impact factor: 11.205

2.  uvrA and recA mutations inhibit a site-specific transition produced by a single O6-methylguanine in gene G of bacteriophage phi X174.

Authors:  R W Chambers; E Sledziewska-Gojska; S Hirani-Hojatti; H Borowy-Borowski
Journal:  Proc Natl Acad Sci U S A       Date:  1985-11       Impact factor: 11.205
  2 in total

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