Literature DB >> 4310476

Polyol pathway in aorta: regulation by hormones.

R S Clements, A D Morrison, A I Winegrad.   

Abstract

Aldose reductase is present in human and rabbit aortas and provides a mechanism whereby hyper-glycemia can alter the metabolism of the arterial wall. Aortic sorbitol concentration is regulated by ambient glucose concentration and is increased by epinephrine, isoproterenol, dibutyryl-3',5'-adenosine monophosphate, ouabain, and angiotensin II.

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Year:  1969        PMID： 4310476     DOI： 10.1126/science.166.3908.1007

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  20 in total

1.  Consumption of polyphenol-rich Morus alba leaves extract attenuates early diabetic retinopathy: the underlying mechanism.

Authors:  Ayman M Mahmoud; Sanaa M Abd El-Twab; Eman S Abdel-Reheim
Journal:  Eur J Nutr       Date:  2016-04-08       Impact factor: 5.614

2.  Effects of fructose ingestion on sorbitol and fructose 3-phosphate contents of erythrocytes from healthy men.

Authors:  M Kawaguchi; T Fujii; Y Kamiya; J Ito; M Okada; N Sakuma; T Fujinami
Journal:  Acta Diabetol       Date:  1996-07       Impact factor: 4.280

3.  Metabolism and oxidation of U- 14 C-glucose, xylitol, fructose and sorbitol in the fasted and in the streptozotocin-diabetic rat.

Authors:  U Keller; E R Froesch
Journal:  Diabetologia       Date:  1971-10       Impact factor: 10.122

4.  The role of carbohydrate and oral agents in the treatment of diabetes mellitus.

Authors:  W D Odell
Journal:  Calif Med       Date:  1973-10

5.  Metabolic alterations in the human erythrocyte produced by increases in glucose concentration. The role of the polyol pathway.

Authors:  S F Travis; A D Morrison; R S Clements; A I Winegrad; F A Oski
Journal:  J Clin Invest       Date:  1971-10       Impact factor: 14.808

6.  The reduction of glyceraldehyde by human erythrocytes. L-hexonate dehydrogenase activity.

Authors:  E Beutler; E Guinto
Journal:  J Clin Invest       Date:  1974-05       Impact factor: 14.808

7.  Chronic exposure to high glucose decreases myo-inositol in cultured cerebral microvascular pericytes but not in endothelium.

Authors:  I Sussman; M P Carson; V Schultz; X P Wu; A L McCall; N B Ruderman; K Tornheim
Journal:  Diabetologia       Date:  1988-10       Impact factor: 10.122

8.  Studies on mechanisms of cerebral edema in diabetic comas. Effects of hyperglycemia and rapid lowering of plasma glucose in normal rabbits.

Authors:  A I Arieff; C R Kleeman
Journal:  J Clin Invest       Date:  1973-03       Impact factor: 14.808

9.  Transport of myo-inositol into endoneurial preparations of sciatic nerve from normal and streptozotocin-diabetic rats.

Authors:  K R Gillon; J N Hawthorne
Journal:  Biochem J       Date:  1983-03-15       Impact factor: 3.857

10.  Myo-inositol and sorbitol metabolism in relation to peripheral nerve function in experimental diabetes in the rat: the effect of aldose reductase inhibition.

Authors:  K R Gillon; J N Hawthorne; D R Tomlinson
Journal:  Diabetologia       Date:  1983-10       Impact factor: 10.122
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