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Literature DB >> 4307880

Propagation of MM virus in L cells.

Abstract

MM virus (mouse-brain stock) replicated to a limited extent in L cells without cytopathic effects; the average yield was less than 1 plaque-forming unit/cell. Passage in BHK-21 cells resulted in MM virus [MM(BHK)] which replicated to high titers (200 to 300 plaque-forming units/cell) in L cells with complete cytopathic effects. Appearance of mature MM(BHK) virus in L-cell cultures begins 4 hr after infection and is completed by 8 hr. Release of mature virus was slow (less than 1% at 8 hr) but was completed by 24 hr.

Entities: Disease Species

Mesh：

Year: 1969 PMID： 4307880 PMCID： PMC377816 DOI： 10.1128/am.17.6.811-814.1969

Source DB: PubMed Journal: Appl Microbiol ISSN： 0003-6919

5 in total

1. Studies on propagation of the Col SK group of viruses in various tissue culture media.

Authors: C W JUNGEBLUT; H KODZA
Journal: Proc Soc Exp Biol Med Date: 1957-10

2. Growth of neurotropic viruses in extraneural tissues. VII. Cultivation of MM and Western equine encephalitis viruses in cultures of rhesus testicular tissue.

Authors: W M SMITH; C A EVANS
Journal: J Immunol Date: 1954-05 Impact factor: 5.422

3. Epidemiological and Experimental Observations on the Possible Significance of Rodents in a Suburban Epidemic of Poliomyelitis.

Authors: C W Jungeblut; G Dalldorf
Journal: Am J Public Health Nations Health Date: 1943-02

4. Neurotropic viruses in extraneural tissues. III. MM virus in human and murine testicular tissues.

Authors: V C CHAMBERS; W M SMITH; C A EVANS
Journal: Proc Soc Exp Biol Med Date: 1951-02

5. Growth of neurotropic viruses in extraneural tissues.

Authors: V C CHAMBERS; W M SMITH; C A EVANS
Journal: J Immunol Date: 1950-12 Impact factor: 5.422

5 in total

6 in total

5. AGM1+ spleen cells contain gamma interferon (IFN-gamma) gene transcripts in the early, sex-dependent production of IFN-gamma after picornavirus infection.

Authors: H I McFarland; N J Bigley
Journal: J Virol Date: 1990-09 Impact factor: 5.103

6. Virus-induced diabetes mellitus in ICR Swiss mice is age dependent.

Authors: D J Giron; S J Cohen; S P Lyons; M L Trombley; C L Gould
Journal: Infect Immun Date: 1983-08 Impact factor: 3.441

6 in total

Propagation of MM virus in L cells.

1. Studies on propagation of the Col SK group of viruses in various tissue culture media.

2. Growth of neurotropic viruses in extraneural tissues. VII. Cultivation of MM and Western equine encephalitis viruses in cultures of rhesus testicular tissue.

3. Epidemiological and Experimental Observations on the Possible Significance of Rodents in a Suburban Epidemic of Poliomyelitis.

4. Neurotropic viruses in extraneural tissues. III. MM virus in human and murine testicular tissues.

5. Growth of neurotropic viruses in extraneural tissues.

1. Rapid sensitive assay for interferons based on the inhibition of MM virus nucleic acid synthesis.

2. Effect of steroid hormones on virus-induced diabetes mellitus.

3. Further studies on the influence of steroids on viral infection in mice.

4. Role of interferon in the propagation of MM virus in L cells.

5. AGM1+ spleen cells contain gamma interferon (IFN-gamma) gene transcripts in the early, sex-dependent production of IFN-gamma after picornavirus infection.

6. Virus-induced diabetes mellitus in ICR Swiss mice is age dependent.