Literature DB >> 4304250

25-Hydroxycholecalciferol: stimulation of bone resorption in tissue culture.

C L Trummel, L G Raisz, J W Blunt, H F Deluca.   

Abstract

25-Hydroxycholecalciferol stimulates release of previously incorporated calcium-45 from fetal rat bones in doses of 0.9 to 27 units per milliliter. This effect cannot be produced by much larger doses of vitamin D(3). Comparison of stimulation of bone resorption by 25-hydroxycholecalciferol and parathyroid hormone reveals similarities with respect to time course, dose-response slope, and inhibition by calcitonin.

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Year:  1969        PMID： 4304250     DOI： 10.1126/science.163.3874.1450

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  29 in total

1.  The effects of 1,25-dihydroxycholecalciferol on embryonic bone in vitro: a biochemical and histological study.

Authors:  M P Herrmann-Erlee; P J Gaillard
Journal:  Calcif Tissue Res       Date:  1978-05-26

2.  Quantitative analyses of osteoclast changes in resorbing bone organ cultures.

Authors:  D J Rowe; E Hausmann
Journal:  Calcif Tissue Res       Date:  1977-10-20

3.  Effects of vitamin D3 metabolites on bone cell calcium transport.

Authors:  R Dziak
Journal:  Calcif Tissue Res       Date:  1978-11-10

4.  Supravalvular aortic stenosis-infantile hypercalcaemia syndrome: in vitro hypersensitivity to vitamin D2 and calcium.

Authors:  D M Becroft; D Chambers
Journal:  J Med Genet       Date:  1976-06       Impact factor: 6.318

Review 5.  Vitamin D-Mediated Hypercalcemia: Mechanisms, Diagnosis, and Treatment.

Authors:  Peter J Tebben; Ravinder J Singh; Rajiv Kumar
Journal:  Endocr Rev       Date:  2016-09-02       Impact factor: 19.871

6.  Lag period of action of 25-hydroxycholecalciferol on bone collagen metabolism in vitamin D deficient rats.

Authors:  E Morava; R Tarjan; M Winter
Journal:  Experientia       Date:  1973-10-15

7.  The role of vitamin D metabolites in bone resorption.

Authors:  J J Reynolds; M F Holick; H F De Luca
Journal:  Calcif Tissue Res       Date:  1973

8.  Effect of renal insufficiency on the active transport of calcium by the small intestine.

Authors:  R D Baerg; D V Kimberg; E Gershon
Journal:  J Clin Invest       Date:  1970-06       Impact factor: 14.808

9.  Metabolism of 25-hydroxyvitamin D3 in anephric rats: a new active metabolite.

Authors:  M Garabedian; H Pavlovitch; C Fellot; S Balsan
Journal:  Proc Natl Acad Sci U S A       Date:  1974-02       Impact factor: 11.205

10.  Calcium-mobilizing effect of large doses of 25-hydroxycholecalciferol in anephric rats.

Authors:  H Pavlovitch; M Garabedian; S Balsan
Journal:  J Clin Invest       Date:  1973-10       Impact factor: 14.808
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