Literature DB >> 4298747

Interferon: protection of cells infected with an intracellular protozoan (Toxoplasma gondii).

J S Remington, T C Merigan.   

Abstract

Chick and mouse cell monolayers treated with interferon were significantly protected from destruction by toxoplasma. The results suggest that fewer numbers of organisms were released from interferon-treated cells. Interferons were uniformly more active in a viral assay than in a toxoplasma assay, and they had the same properties in both assays. The data suggest that interferon activity may be directed against organisms phylogenetically higher than viruses.

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Year:  1968        PMID： 4298747     DOI： 10.1126/science.161.3843.804

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  39 in total

1.  Interferon production in mixed lymphocyte cell cultures.

Authors:  G E Gifford; A Tibor; D L Peavy
Journal:  Infect Immun       Date:  1971-01       Impact factor: 3.441

2.  Recombinant human gamma interferon inhibits simian malaria.

Authors:  R K Maheshwari; C W Czarniecki; G P Dutta; S K Puri; B N Dhawan; R M Friedman
Journal:  Infect Immun       Date:  1986-09       Impact factor: 3.441

3.  Synthesis and secretion of interferon by murine fibroblasts in response to intracellular Listeria monocytogenes.

Authors:  E A Havell
Journal:  Infect Immun       Date:  1986-12       Impact factor: 3.441

4.  The stimulation by endotoxin of the nonspecific resistance of mice to bacterial infections.

Authors:  A W Hill; K G Hibbitt; A Shears
Journal:  Br J Exp Pathol       Date:  1974-04

Review 5.  Current status of toxoplasma and toxoplasmosis: a review.

Authors:  P J Quinn; B M McCraw
Journal:  Can Vet J       Date:  1972-11       Impact factor: 1.008

6.  Nonspecific protective action against Vibrio cholerae of SK&F 42319, a ribonucleic acid obtained from bacteriophage-infected Escherichia coli.

Authors:  P Actor; D Pitkin; M Y Goore; L J Berry
Journal:  Infect Immun       Date:  1972-11       Impact factor: 3.441

7.  Plaquing of Toxoplasma gondii in secondary cultures of chick embryo fibroblasts.

Authors:  V L Foley; J S Remington
Journal:  J Bacteriol       Date:  1969-04       Impact factor: 3.490

8.  Interferon gamma blocks the growth of Toxoplasma gondii in human fibroblasts by inducing the host cells to degrade tryptophan.

Authors:  E R Pfefferkorn
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

9.  Mouse fibroblast interferon modifies Salmonella typhimurium infection in infant mice.

Authors:  G Bukholm; B P Berdal; C Haug; M Degré
Journal:  Infect Immun       Date:  1984-07       Impact factor: 3.441

10.  Killing of intracellular Leishmania donovani by lymphokine-stimulated human mononuclear phagocytes. Evidence that interferon-gamma is the activating lymphokine.

Authors:  H W Murray; B Y Rubin; C D Rothermel
Journal:  J Clin Invest       Date:  1983-10       Impact factor: 14.808
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