| Literature DB >> 3091507 |
R K Maheshwari, C W Czarniecki, G P Dutta, S K Puri, B N Dhawan, R M Friedman.
Abstract
Prophylactic treatment with 0.1 mg of human gamma interferon per kg (body weight) per day completely suppressed experimental infection with Plasmodium cynomolgi B sporozoites in rhesus monkeys. Treatment with lower doses partially suppressed this infection. Prophylactic treatment with human gamma interferon, however, had no protective effect against trophozoite-induced infection, suggesting that the interferon effect was limited to the exoerythrocytic stage of parasitic development.Entities:
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Year: 1986 PMID: 3091507 PMCID: PMC260838 DOI: 10.1128/iai.53.3.628-630.1986
Source DB: PubMed Journal: Infect Immun ISSN: 0019-9567 Impact factor: 3.441