Literature DB >> 4293665

Avirulent Clostridium perfringens strains obtained by euflavine treatment.

G Paquette, V Fredette.   

Abstract

Clostridium perfringens was incubated in the presence of euflavine (EU); the resistant mutants which were thus isolated had highly reduced capacity to release alpha-toxin. This fact was confirmed by lecithinase determinations and by immunoelectrophoresis. Injected into guinea pigs and into 6- to 7-day-old chicks, these mutants were completely avirulent. A study of their properties indicated biochemical differences between wild types and mutants.

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Year:  1967        PMID: 4293665      PMCID: PMC276844          DOI: 10.1128/jb.94.5.1437-1442.1967

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  8 in total

1.  Use of the Waring blendor for reducing the viscosity of fluid cultures of the perfringens bacillus.

Authors:  V FREDETTE; G VINET
Journal:  Can J Microbiol       Date:  1962-04       Impact factor: 2.419

2.  Acriflavine as an effective agent for eliminating F-factor in Escherichia coli K-12.

Authors:  Y HIROTA; T LIJIMA
Journal:  Nature       Date:  1957-09-28       Impact factor: 49.962

3.  Genetic studies on microbial cross resistance to toxic agents. I. Cross resistance of Escherichia coli to fifteen antibiotics.

Authors:  W SZYBALSKI; V BRYSON
Journal:  J Bacteriol       Date:  1952-10       Impact factor: 3.490

4.  The biochemistry of the gas gangrene toxins: Estimation of the alpha toxin of Cl. welchii, type A.

Authors:  W E Van Heyningen
Journal:  Biochem J       Date:  1941-11       Impact factor: 3.857

5.  The biochemistry of bacterial toxins: The lecithinase activity of Cl. welchii toxins.

Authors:  M G Macfarlane; B C Knight
Journal:  Biochem J       Date:  1941-09       Impact factor: 3.857

6.  The biochemistry of the gas gangrene toxins: Partial purification of the toxins of Cl. welchii, type A. Separation of alpha and theta toxins.

Authors:  W E Van Heyningen
Journal:  Biochem J       Date:  1941-11       Impact factor: 3.857

7.  The isolation of the alpha-toxin of Clostridium welchii type A by zone electrophoresis in vertical columns.

Authors:  J Stephen
Journal:  Biochem J       Date:  1961-09       Impact factor: 3.857

8.  [Effect of acriflavine on yeasts. VIII. Determination of the active component and study of euflavine].

Authors:  H MARCOVICH
Journal:  Ann Inst Pasteur (Paris)       Date:  1951-10
  8 in total
  6 in total

1.  Isolation and characterization of Clostridium perfringens mutants altered in both hemagglutinin and sialidase production.

Authors:  J I Rood; R G Wilkinson
Journal:  J Bacteriol       Date:  1975-08       Impact factor: 3.490

2.  Correlations between virulence and other characters of Clostridium perfringens type A.

Authors:  A Forget; G Paquette; A Roy; V Fredette
Journal:  Appl Microbiol       Date:  1969-10

3.  Lecithinase activity of mutant and wild strains of Clostridium perfringens.

Authors:  J A Schulze; M Nakamura
Journal:  Appl Microbiol       Date:  1968-10

Review 4.  Sporulation and the production of antibiotics, exoenzymes, and exotonins.

Authors:  P Schaeffer
Journal:  Bacteriol Rev       Date:  1969-03

5.  [Necrotic enteritis in broilers. II. Characteristics of the strains of Clostridium perfringens isolated].

Authors:  G Bernier; R Filion; R Malo; J B Phaneuf
Journal:  Can J Comp Med       Date:  1974-07

6.  Probing Genomic Aspects of the Multi-Host Pathogen Clostridium perfringens Reveals Significant Pangenome Diversity, and a Diverse Array of Virulence Factors.

Authors:  Raymond Kiu; Shabhonam Caim; Sarah Alexander; Purnima Pachori; Lindsay J Hall
Journal:  Front Microbiol       Date:  2017-12-12       Impact factor: 5.640

  6 in total

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