Literature DB >> 429124

On the possible role of glycosaminoglycans as natural inhibitors of calcium oxalate stones.

J D Sallis, M F Lumley.   

Abstract

An extract of glycosaminoglycans was prepared from normal urine and components fractionated by electrophoresis on Vinylite support medium. Several fractions displayed an ability to inhibit formation of calcium oxalate crystals in vitro. Inasmuch as well recognized urinary glycosaminoglycans such as chondroitin sulfates and hyaluronic acid must contribute to the urine inhibitory power, an unknown material was isolated with potent inhibitory properties. The material contained little detectable uronic acid of hexosamine and had a molecular weight greater than 10,000.

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Year:  1979        PMID： 429124

Source DB:  PubMed          Journal:  Invest Urol        ISSN： 0021-0005


  9 in total

1.  Urinary crystal surface binding substances on calcium oxalate crystals.

Authors:  T Koide; T Yoshioka; S Yamaguchi; S Hosokawa; M Utsunomiya; T Sonoda
Journal:  Urol Res       Date:  1990

2.  An unidentified macromolecular inhibitory constituent of calcium oxalate crystal growth in human urine.

Authors:  S Sørensen; K Hansen; S Bak; S J Justesen
Journal:  Urol Res       Date:  1990

3.  Investigation of GAGS on 24-hour and 2-hour urines from calcium oxalate stone formers and healthy subjects.

Authors:  M Gianotti; C Genestar; A Palou; A Pons; A Conte; F Grases
Journal:  Int Urol Nephrol       Date:  1989       Impact factor: 2.370

Review 4.  Glycosaminoglycans, proteins, and stone formation: adult themes and child's play.

Authors:  R L Ryall
Journal:  Pediatr Nephrol       Date:  1996-10       Impact factor: 3.714

Review 5.  The scientific basis of calcium oxalate urolithiasis. Predilection and precipitation, promotion and proscription.

Authors:  R L Ryall
Journal:  World J Urol       Date:  1993       Impact factor: 4.226

6.  Evaluation of the relative inhibitory potential of fractionated urinary macromolecules.

Authors:  R Azoury; B Goldwasser; Y Wax; S Perlberg; N Garti; S Sarig
Journal:  Urol Res       Date:  1985

7.  Heparin sulfate in the stone matrix and its inhibitory effect on calcium oxalate crystallization.

Authors:  S Yamaguchi; T Yoshioka; M Utsunomiya; T Koide; M Osafune; A Okuyama; T Sonoda
Journal:  Urol Res       Date:  1993-05

8.  Scanning electron microscopy and molecular modeling of inhibition of calcium oxalate monohydrate crystal growth by citrate and phosphocitrate.

Authors:  A Wierzbicki; C S Sikes; J D Sallis; J D Madura; E D Stevens; K L Martin
Journal:  Calcif Tissue Int       Date:  1995-04       Impact factor: 4.333

9.  Effects of chondroitin sulphate, human serum albumin and Tamm-Horsfall mucoprotein on calcium oxalate crystallization in undiluted human urine.

Authors:  R L Ryall; R M Harnett; C M Hibberd; K A Edyvane; V R Marshall
Journal:  Urol Res       Date:  1991
  9 in total

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