Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.

Literature DB >> 4276359

Genetic control of alkaline phosphatase synthesis in Neurospora: the use of partial diploids in dominance studies.

R L Metzenberg, M K Gleason, B S Littlewood.

Abstract

In wild-type Neurospora, alkaline phosphatase is made under conditions of phosphate limitation, but not conditions of phosphate sufficiency. Mutants at two unlinked loci, nuc-1 and nuc-2, do not make alkaline phosphatase under any conditions, while mutants at two quite closely linked loci, pcon and preg, make alkaline phosphatase even under conditions of phosphate sufficiency. pcon is extremely closely linked to nuc-2. nuc-2 and preg(c) (constitutive) mutants are recessive to their wild-type alleles in partial diploids as well as in heterokaryons, while pcon(c) mutants are dominant or co-dominant. nuc-1 is epistatic to both pcon(c) and preg(c) mutants. The implications of these findings for theories of metabolic control in eukaryotes are briefly discussed.

Entities: Chemical Gene

Mesh：

Substances：
Alkaline Phosphatase

Year: 1974 PMID： 4276359 PMCID： PMC1213116

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

10 in total

1. A rapid method for obtaining unordered Neurospora tetrads.

Authors: W N STRICKLAND
Journal: J Gen Microbiol Date: 1960-04

2. Genetic control of the synthesis of repressible phosphatases in Neurospora crassa.

Authors: A Toh-E; T Ishikawa
Journal: Genetics Date: 1971-11 Impact factor: 4.562

3. Regulation of phosphate metabolism in Neurospora crassa. Characterization of regulatory mutants.

Authors: J F Lehman; M K Gleason; S K Ahlgren; R L Metzenberg
Journal: Genetics Date: 1973-09 Impact factor: 4.562

4. Chemical induction of mitotic recombination in Aspergillus nidulans.

Authors: B Shanfield; E Käfer
Journal: Genetics Date: 1971-02 Impact factor: 4.562

5. The product of the leu-3 cistron as a regulatory element for the production of the leucine biosynthetic enzymes of Neurospora.

Authors: J C Polacco; S R Gross
Journal: Genetics Date: 1973-07 Impact factor: 4.562

6. Isolation and characterization of nuclease mutants in Neurospora crassa.

Authors: T Ishikawa; A Toh-E; I Uno; K Hasunuma
Journal: Genetics Date: 1969-09 Impact factor: 4.562

7. Mutants in the arom gene cluster of Neurospora crassa specific for biosynthetic dehydroquinase.

Authors: H W Rines; M E Case; N H Giles
Journal: Genetics Date: 1969-04 Impact factor: 4.562

8. New duplication-generating inversions in Neurospora.

Authors: B C Turner; C W Taylor; D D Perkins; D Newmeyer
Journal: Can J Genet Cytol Date: 1969-09

9. A test of coincident recombination in closely linked genes of Neurospora.

Authors: D R Stadler; A M Towe
Journal: Genetics Date: 1968-03 Impact factor: 4.562

10. Constitutive mutants in a regulatory gene exerting positive control of quinic acid catabolism in Neurospora crassa.

Authors: J A Valone; M E Case; N H Giles
Journal: Proc Natl Acad Sci U S A Date: 1971-07 Impact factor: 11.205

10 in total

15 in total

1. Genetic control of phosphate-metabolizing enzymes in Neurospora crassa: relationships among regulatory mutations.

Authors: B S Littlewood; W Chia; R L Metzenberg
Journal: Genetics Date: 1975-03 Impact factor: 4.562

2. Control of the activity of intracellular nucleases in Neurospora crassa.

Authors: K Hasunuma
Journal: Mol Gen Genet Date: 1978-04-17

3. Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible acid phosphatase.

Authors: R E Nelson; J F Lehman; R L Metzenberg
Journal: Genetics Date: 1976-10 Impact factor: 4.562

4. Regulation of phosphate metabolism in Neurospora crassa: identification of the structural gene for repressible alkaline phosphatase.

Authors: J F Lehman; R L Metzenberg
Journal: Genetics Date: 1976-10 Impact factor: 4.562

9. Regulation of phosphate metabolism in Neurospora crassa: isolation of mutants deficient in ther repressible alkaline phosphatase.

Authors: M K Gleason; R L Metzenberg
Journal: Genetics Date: 1974-10 Impact factor: 4.562

10. Control of the Production of orthophosphate repressible extracellular enzymes in Neurospora crassa.

Authors: K Hasunuma
Journal: Mol Gen Genet Date: 1977-02-28