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Literature DB >> 4258952

The requirement for platelets in the active Arthus reaction.

Abstract

The active Arthus reaction was completely inhibited in rabbits made thrombocytopenic with platelet antiserum. Platelets or some platelet factor is necessary for the development of immune vasculitis in this model. Since the classic Arthus reaction depends on the union of extravascular antigen with intravascular antibody, it is probable that the missing platelet factor is an agent that alters vascular permeability.

Entities: Disease Species

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Year: 1971 PMID： 4258952 PMCID： PMC2047577

Source DB: PubMed Journal: Am J Pathol ISSN： 0002-9440 Impact factor: 4.307

13 in total

1. Studies of aggregated gamma-globulin. I. Sedimentation, electrophoretic and anticomplementary properties.

Authors: C L CHRISTIAN
Journal: J Immunol Date: 1960-01 Impact factor: 5.422

2. The mechanism of Arthus reactions. II. The role of polymorphonuclear leucocytes and platelets in reversed passive reactions in the guinea-pig.

Authors: J H HUMPHREY
Journal: Br J Exp Pathol Date: 1955-06

3. The mechanism of Arthus reactions. I. The role of polymorphonuclear leucocytes and other factors in reversed passive Arthus reactions in rabbits.

Authors: J H HUMPHREY
Journal: Br J Exp Pathol Date: 1955-06

4. The histamine and serotonin content of the platelets and polymorphonuclear leucocytes of various species.

Authors: J H HUMPHREY; R JAQUES
Journal: J Physiol Date: 1954-05-28 Impact factor: 5.182

5. Ultrastructure of the local Arthus phenomenon using horseradish peroxidase as antigen.

Authors: M A Venkatachalam; R S Cotran
Journal: Lab Invest Date: 1970-08 Impact factor: 5.662

6. The localization of circulating immune complexes in experimental serum sickness. The role of vasoactive amines and hydrodynamic forces.

Authors: W T Kniker; C G Cochrane
Journal: J Exp Med Date: 1968-01-01 Impact factor: 14.307

7. The role of the platelet in the generalized Shwartzman reaction.

Authors: W Margaretten; D G McKay
Journal: J Exp Med Date: 1969-03-01 Impact factor: 14.307

8. BOUND COMPLEMENT AND IMMUNOLOGIC INJURY OF BLOOD VESSELS.

Authors: P A WARD; C G COCHRANE
Journal: J Exp Med Date: 1965-02-01 Impact factor: 14.307

9. THE ROLE OF SERUM COMPLEMENT IN CHEMOTAXIS OF LEUKOCYTES IN VITRO.

Authors: P A WARD; C G COCHRANE; H J MUELLER-EBERHARD
Journal: J Exp Med Date: 1965-08-01 Impact factor: 14.307

10. The role of polymorphonuclear leukocytes in the initiation and cessation of the Arthus vasculitis.

Authors: C G COCHRANE; W O WEIGLE; F J DIXON
Journal: J Exp Med Date: 1959-09-01 Impact factor: 14.307

13 in total

1. Effects of intravascular clotting on the activation of the complement system: The role of the platelet.

Authors: S Kalowski; E L Howes; W Margaretten; D G McKay
Journal: Am J Pathol Date: 1975-03 Impact factor: 4.307

2. The effect of shock on the inflammatory response. A reevaluation of the role of platelets in the active arthus reaction.

Authors: W Margaretten; E L Howes; D G McKay
Journal: Am J Pathol Date: 1975-01 Impact factor: 4.307

3. Platelets, acute inflammation and inflammatory mediators.

Authors: S H Ferreira; F B Ubatuba; J R Vane
Journal: Agents Actions Date: 1976-02

4. Accumulation of platelets at acute inflammatory sites [proceedings].

Authors: J P Bolam; M J Smith
Journal: Br J Pharmacol Date: 1977-09 Impact factor: 8.739

5. The participation of the platelet in the vascular response to endotoxemia in the rabbit eye.

Authors: E L Howes; D G McKay; W Margaretten
Journal: Am J Pathol Date: 1973-01 Impact factor: 4.307

6. Blood platelets and the inflammatory process.

Authors: M J Silver; J B Smith; C M Ingerman
Journal: Agents Actions Date: 1974-10

7. Arthus synovitis with horseradish peroxidase as antigen: sequential participation of platelets and leucocytes.

Authors: R C Graham; R Griffin
Journal: Br J Exp Pathol Date: 1972-10

Review 8. Platelets, thrombosis and drugs.

Authors: J F Mustard; M A Packham
Journal: Drugs Date: 1975 Impact factor: 9.546

9. Platelets, fibroblasts, and inflammation: tissue reactions to platelets injected subcutaneously.

Authors: P W Braunstein; H F Cuénoud; I Joris; G Majno
Journal: Am J Pathol Date: 1980-04 Impact factor: 4.307

10. Platelets, prostaglandins and inflammation.

Authors: M J Smith; J R Walker; A W Ford-Hutchinson; D G Penington
Journal: Agents Actions Date: 1976-11