Literature DB >> 4247779

Glycolytic enzymes in adipose tissue of adult diabetics.

D J Galton, J P Wilson.   

Abstract

The maximal activities of hexokinase and phosphofructokinase were measured in human adipose tissue. Though the mean activity of hexokinase was similar between a group of adult diabetics (n=24) and a group of non-diabetic controls (n=25), in the diabetic group the activity of phosphofructokinase was definitely reduced. Possibly this enzyme deficiency might contribute to impaired glucose utilization by the adipose cell in diabetes.

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Year:  1970        PMID： 4247779      PMCID： PMC1701411          DOI： 10.1136/bmj.3.5720.444

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  9 in total

1.  New type of needle for obtaining large samples of human adipose tissue.

Authors:  D Diengott; S Kerpel
Journal:  J Lipid Res       Date:  1967-01       Impact factor: 5.922

2.  ENZYME PATTERNS IN HUMAN TISSUES. II. GLYCOLYTIC ENZYME PATTERNS IN NONMALIGNANT HUMAN TISSUES.

Authors:  C E SHONK; B J KOVEN; H MAJIMA; G E BOXER
Journal:  Cancer Res       Date:  1964-05       Impact factor: 12.701

3.  THE EFFECT OF INSULIN ON HUMAN ADIPOSE TISSUE.

Authors:  A KAHLENBERG; N KALANT
Journal:  Can J Biochem       Date:  1964-11

4.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

5.  The effect of diabetes and insulin in vivo and in vitro on a low Km form of hexokinase from various rat tissues.

Authors:  H M Katzen
Journal:  Biochem Biophys Res Commun       Date:  1966-08-23       Impact factor: 3.575

6.  Effect of alloxan-diabetes on multiple forms of hexokinase in adipose tissue and lung.

Authors:  P McLean; J Brown; E Walters; K Greenslade
Journal:  Biochem J       Date:  1967-12       Impact factor: 3.857

7.  Insulin-resistant diabetes associated with increased endogenous plasma insulin followed by complete remission.

Authors:  J B FIELD; P JOHNSON; B HERRING
Journal:  J Clin Invest       Date:  1961-09       Impact factor: 14.808

8.  Defect in glucose utilization in adipose tissue of patients with maturity-onset diabetes.

Authors:  D J Galton; J P Wilson
Journal:  Br Med J       Date:  1969-03-08

9.  A defect of glucose utilization in adipose tissue of adult diabetics and in some conditions which may predispose to diabetes.

Authors:  D J Galton; J P Wilson
Journal:  Clin Sci       Date:  1970-06       Impact factor: 6.124
  9 in total
  2 in total

1.  Increased lipid synthesis by liver slice in a superfusion system following raised glucose or insulin concentration.

Authors:  B R Tulloch; K Dyal; T R Fraser
Journal:  Diabetologia       Date:  1972-08       Impact factor: 10.122

2.  Insulin-independent diabetes: a defect in the activity of lipoprotein lipase in adipose tissue.

Authors:  K G Taylor; D J Galton; G Holdsworth
Journal:  Diabetologia       Date:  1979-05       Impact factor: 10.122
  2 in total

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