Literature DB >> 424002

Supersensitivity to opioids following the chronic blockade of endorphin action by naloxone.

R Schulz, M Wüster, A Herz.   

Abstract

Chronic treatment of guinea pigs with the narcotic antagonist naloxone (pellet implantation technique) caused an increased sensitivity to opioids of the electrically stimulated longitudinal muscle-myenteric plexus preparation of the ileum. This supersensitivity is associated with an elevation of the total number of opiate receptor binding sites in both the peripheral and the central nervous system.

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Year:  1979        PMID： 424002     DOI： 10.1007/bf00515600

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN： 0028-1298            Impact factor:   3.000


  16 in total

1.  The effect of N-allylnormorphine upon the development of tolerance to morphine in the albino rat.

Authors:  P D ORAHOVATS; C A WINTER; E G LEHMAN
Journal:  J Pharmacol Exp Ther       Date:  1953-12       Impact factor: 4.030

2.  Enhanced analgesic effects of morphine after chronic administration of naloxone in the rat.

Authors:  A H Tang; R J Collins
Journal:  Eur J Pharmacol       Date:  1978-02-15       Impact factor: 4.432

3.  Binding of 3H-naloxone in the mouse brain: effect of ions and tolerance development.

Authors:  R J Hitzemann; B A Hitzemann; H H Loh
Journal:  Life Sci       Date:  1974-06-16       Impact factor: 5.037

4.  Behavioral effects of separate and combined administration of naloxone and d-amphetamine.

Authors:  S G Holtzman
Journal:  J Pharmacol Exp Ther       Date:  1974-04       Impact factor: 4.030

5.  Inactivity of narcotic glucuronides as analgesics and on guinea-pig ileum.

Authors:  R Schulz; A Goldstein
Journal:  J Pharmacol Exp Ther       Date:  1972-11       Impact factor: 4.030

6.  Formulation of a morphine implantation pellet suitable for tolerance-physical dependence studies in mice.

Authors:  R D Gibson; J E Tingstad
Journal:  J Pharm Sci       Date:  1970-03       Impact factor: 3.534

7.  The relationship between pharmacokinetics and pharmacodynamic action as applied to in vivo pA2: application to the analgesic effect of morphine.

Authors:  R J Tallarida; C Harakal; J Maslow; E B Geller; M W Adler
Journal:  J Pharmacol Exp Ther       Date:  1978-07       Impact factor: 4.030

8.  The distribution of methionine-enkephalin and leucine-enkephalin in the brain and peripheral tissues.

Authors:  J Hughes; H W Kosterlitz; T W Smith
Journal:  Br J Pharmacol       Date:  1977-12       Impact factor: 8.739

9.  Kinetic parameters of narcotic agonists and antagonists, with particular reference to N-allylnoroxymorphone (naloxone).

Authors:  H W Kosterlitz; A J Watt
Journal:  Br J Pharmacol Chemother       Date:  1968-06

Review 10.  Dopamine receptors in the central nervous system.

Authors:  P Seeman; J L Tedesco; T Lee; M Chau-Wong; P Muller; J Bowles; P M Whitaker; C McManus; M Tittler; P Weinreich; W C Friend; G M Brown
Journal:  Fed Proc       Date:  1978-02
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  10 in total

1.  Increased sensitivity to rate-altering and discriminative stimulus effects of morphine following continuous exposure to naltrexone.

Authors:  A M Young; S R Mattox; M D Doty
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

2.  Irving Page Lecture: 5-HT(2A) serotonin receptor biology: interacting proteins, kinases and paradoxical regulation.

Authors:  Bryan L Roth
Journal:  Neuropharmacology       Date:  2011-02-01       Impact factor: 5.250

Review 3.  Opioid mechanisms in insects, with special attention to Leucophaea maderae.

Authors:  B Scharrer; G B Stefano; M K Leung
Journal:  Cell Mol Neurobiol       Date:  1988-09       Impact factor: 5.046

4.  Centrally and peripherally mediated inhibition of intestinal motility by opioids.

Authors:  R Schulz; M Wüster; A Herz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1979-09       Impact factor: 3.000

5.  Visualization of opiate receptor upregulation by light microscopy autoradiography.

Authors:  A Tempel; E L Gardner; R S Zukin
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

6.  Diprenorphine and naloxone in squirrel monkeys with enhanced sensitivity to opioid antagonists.

Authors:  A H Oliveto; L A Dykstra
Journal:  Psychopharmacology (Berl)       Date:  1988       Impact factor: 4.530

7.  Feed-back effect of growth hormone on hypothalamic opioid and somatocrinin producing neurons.

Authors:  I Ganzetti; F Petraglia; I Capuano; F Rosi; W B Wehrenberg; E E Müller; D Cocchi
Journal:  J Endocrinol Invest       Date:  1987-06       Impact factor: 4.256

Review 8.  Opioid Receptor-Mediated and Non-Opioid Receptor-Mediated Roles of Opioids in Tumour Growth and Metastasis.

Authors:  Claudia A Scroope; Zane Singleton; Markus W Hollmann; Marie-Odile Parat
Journal:  Front Oncol       Date:  2021-12-23       Impact factor: 6.244

9.  The effects of maternally administered methadone, buprenorphine and naltrexone on offspring: review of human and animal data.

Authors:  W O Farid; S A Dunlop; R J Tait; G K Hulse
Journal:  Curr Neuropharmacol       Date:  2008-06       Impact factor: 7.363

10.  Exposure to exogenous enkephalins disrupts reproductive development in the Eastern lubber grasshopper, Romalea microptera (Insecta: Orthoptera).

Authors:  Sandeep Kumar; Ganji Purnachandra Nagaraju; Purnachandra Nagaraju Ganji; Hojun Song; Laurence von Kalm; David W Borst
Journal:  PLoS One       Date:  2012-11-30       Impact factor: 3.240
  10 in total

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