| Literature DB >> 423006 |
M S Donnell, G A Meyer, W L Donegan.
Abstract
The increased frequency of meningiomas in women compared with men, and the rapidly progressive course of these tumors in pregnant patients suggest that hormones may be involved in this disease. Tumor tissue from six patients with meningiomas was analyzed for estrogen-receptor protein. Two patients had tumors with very high concentrations of this protein, approaching that found in hormonally sensitive breast carcinoma. The biochemical and possible clinical significance of these findings is discussed.Entities:
Keywords: Biology; Cancer--etiology; Clinical Research; Diseases; Endocrine System; Estradiol; Estrogens; Histology; Hormone Receptors--analysis; Hormones; In Vitro; Laboratory Procedures; Membrane Proteins; Men; Neoplasms; Physiology; Research Methodology; Women
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Year: 1979 PMID： 423006 DOI： 10.3171/jns.1979.50.4.0499
Source DB: PubMed Journal: J Neurosurg ISSN： 0022-3085 Impact factor: 5.115