Literature DB >> 4228706

Salicylanilides: a new group of active uncouplers of oxidative phosphorylation.

R L Williamson, R L Metcalf.   

Abstract

Investigations using housefly mitochondria revealed several salicylanilide derivatives as the most effective uncoupling agents of oxidative phosphorylation reported so far. Even greater inhibition of the associated P(i)-adenosine triphosphate exchange was shown with these compounds in both housefly and rat-liver mitochondria, and close similarity was observed between the two types of organelles.

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Year:  1967        PMID： 4228706     DOI： 10.1126/science.158.3809.1694

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  18 in total

1.  The effect of the polar moiety of lipids on bilayer conductance induced by uncouplers of oxidative phosphorylation.

Authors:  U Hopfer; A L Lehninger; W J Lennarz
Journal:  J Membr Biol       Date:  1970-12       Impact factor: 1.843

2.  Factors affecting the susceptibility of staphylococci to killing by the cationic proteins from rabbit polymorphonuclear leucocytes: the effects of alteration of cellular energetics and of various iron compounds.

Authors:  E Walton; G P Gladstone
Journal:  Br J Exp Pathol       Date:  1976-10

3.  [Concepts for the synthesis of new biologically active substances].

Authors:  K H Büchel
Journal:  Naturwissenschaften       Date:  1979-04

4.  Pesticidal chemicals affecting some energy-linked functions of rat liver mitochondria in vitro.

Authors:  N Abo-Khatwa; R M Hollingworth
Journal:  Bull Environ Contam Toxicol       Date:  1974-10       Impact factor: 2.151

5.  K+-independent effects of valinomycin in photosynthetic systems.

Authors:  D L Keister; N J Minton
Journal:  J Bioenerg       Date:  1970-10

6.  A new concept for energy coupling in oxidative phosphorylation based on a molecular explanation of the oxygen exchange reactions.

Authors:  P D Boyer; R L Cross; W Momsen
Journal:  Proc Natl Acad Sci U S A       Date:  1973-10       Impact factor: 11.205

7.  Identification of novel triazole inhibitors of Wnt/β-catenin signaling based on the Niclosamide chemotype.

Authors:  Robert A Mook; Jiangbo Wang; Xiu-Rong Ren; Hailan Piao; H Kim Lyerly; Wei Chen
Journal:  Bioorg Med Chem Lett       Date:  2018-11-12       Impact factor: 2.823

8.  2-Halogeno-ethanols as an uncoupler of phosphorylation in rat liver mitochondria.

Authors:  S Ebina; Y Nagai
Journal:  Experientia       Date:  1980-05-15

Review 9.  Targeting Phenotypically Tolerant Mycobacterium tuberculosis.

Authors:  Ben Gold; Carl Nathan
Journal:  Microbiol Spectr       Date:  2017-01

10.  Inhibition of membrane transport in Streptococcus faecalis by uncouplers of oxidative phosphorylation and its relationship to proton conduction.

Authors:  F M Harold; J R Baarda
Journal:  J Bacteriol       Date:  1968-12       Impact factor: 3.490
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