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Literature DB >> 4209117

Sex-linked auxotrophic and putative auxotrophic mutants of Drosophila melanogaster.

Abstract

Thirty-two mutants with improved growth response on a yeast-sucrose compared with a defined medium have been characterized with respect to ribonucleoside supplementability. Twenty mutants respond to either pyrimidine ribonucleoside. Four mutants respond to one or both purine ribonucleosides. Eight mutants ("putative" auxotrophs) do not respond to dietary RNA supplementation. Mapping and complementation studies suggest that eleven loci are represented: one, rudimentary, probably accounts for all pyrimidine requirers; there are three purine loci and seven at which the putative auxotrophs are found.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1974 PMID： 4209117 PMCID： PMC1213102

Source DB: PubMed Journal: Genetics ISSN： 0016-6731 Impact factor: 4.562

14 in total

2. Studies on the female sterile mutant rudimentary of Drosophila melanogaster. II. An analysis of aspartate transcarbamylase and dihydroorotase activities in wild-type and rudimentary strains.

Authors: A Fausto-Sterling
Journal: Biochem Genet Date: 1977-08 Impact factor: 1.890

Review 3. Genetics and biochemistry of carbamoyl phosphate biosynthesis and its utilization in the pyrimidine biosynthetic pathway.

Authors: A J Makoff; A Radford
Journal: Microbiol Rev Date: 1978-06

7. Phosphonacetyl-L-aspartate: an aspartate transcarbamylase inhibitor causing larval death and rudimentary wing phenocopies in Drosophila melanogaster.

Authors: B J Holaday; J W Fristrom
Journal: Experientia Date: 1977-04-15

8. The raspberry locus encodes Drosophila inosine monophosphate dehydrogenase.

Authors: R Slee; M Bownes
Journal: Mol Gen Genet Date: 1995-10-25

9. Pyrimidine auxotrophy and the complementation map of the rudimentary locus of Drosophila melanogaster.

Authors: D R Falk
Journal: Mol Gen Genet Date: 1976-10-18

10. Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides.

Authors: F N Naguib; D Nash
Journal: Mol Gen Genet Date: 1976-08-10

Sex-linked auxotrophic and putative auxotrophic mutants of Drosophila melanogaster.

1. Complementation among the subgenic mutants in the r-locus of Drosophila melangogaster.

2. Conversion of 2-amino-4-hydroxypteridine to isoxanthopterin in D. Melanogaster.

3. Genetic Control of Biochemical Reactions in Neurospora.

4. Development of Eye Colors in Drosophila: Diffusible Substances and Their Interrelations.

5. Cytological localization of DNA complementary to ribosomal RNA in polytene chromosomes of Diptera.

6. Nutritional conditional mutants of Drosophila melanogaster.

7. The anatomy and function of a segment of the X chromosome of Drosophila melanogaster.

8. A purine and pyrimidine requiring mutant of Drosophila melanogaster.

9. Segmental aneuploidy as a probe for structural genes in Drosophila: mitochondrial membrane enzymes.

10. Chemical selection of alcohol dehydrogenase negative mutants in drosophila.

1. Two Drosophila melanogaster mutations block successive steps of de novo purine synthesis.

2. Studies on the female sterile mutant rudimentary of Drosophila melanogaster. II. An analysis of aspartate transcarbamylase and dihydroorotase activities in wild-type and rudimentary strains.

Review 3. Genetics and biochemistry of carbamoyl phosphate biosynthesis and its utilization in the pyrimidine biosynthetic pathway.

4. Genetic and biochemical properties of revertants at the rudimentary locus in Drosophila melanogaster.

5. Three purine auxotrophic loci on the second chromosome of Drosophila melanogaster.

6. Modifier of rudimentary p1, mod(r)p1, a trans-acting regulatory mutation of rudimentary.

7. Phosphonacetyl-L-aspartate: an aspartate transcarbamylase inhibitor causing larval death and rudimentary wing phenocopies in Drosophila melanogaster.

8. The raspberry locus encodes Drosophila inosine monophosphate dehydrogenase.

9. Pyrimidine auxotrophy and the complementation map of the rudimentary locus of Drosophila melanogaster.

10. Nucleoside auxotrophy in Drosophila: an autosomal locus yielding mutants supplementable by purine and pyrimidine ribonucleosides.