Literature DB >> 4196583

The mechanism of the antihypertensive action of -methyldopa in hypertensive rats.

M D Day, A G Roach, R L Whiting.   

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Year:  1973        PMID: 4196583     DOI: 10.1016/0014-2999(73)90126-x

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN: 0014-2999            Impact factor:   4.432


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  12 in total

1.  On the role of alpha-methyldopamine in the antihypertensive effect of alpha-methyldopa.

Authors:  P Waldmeier; P R Hedwal; L Maître
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  alpha-Methyldopa produces mydriasis in the rat by stimulation of CNS alpha 2-adrenoceptors.

Authors:  J A Hey; T Ito; M C Koss
Journal:  Br J Pharmacol       Date:  1988-07       Impact factor: 8.739

Review 3.  Antihypertensive drugs: clinical pharmacology and therapeutic use.

Authors:  G L Wollam; R W Gifford; R C Tarazi
Journal:  Drugs       Date:  1977-12       Impact factor: 9.546

4.  Central alpha- and beta-adrenoceptors modifying arterial blood pressure and heart rate in conscious cats.

Authors:  M D Day; A G Roach
Journal:  Br J Pharmacol       Date:  1974-07       Impact factor: 8.739

5.  Hypotensive activity of S-alpha-methyldopa during long-term (steady-state) intravenous infusions.

Authors:  P D Walson; J Pesout; R P Forsyth; N Castagnoli; K L Melmon
Journal:  J Pharmacokinet Biopharm       Date:  1976-10

6.  Mechanism of L-alpha-methyldopa transport through a monolayer of polarized human intestinal epithelial cells (Caco-2).

Authors:  M Hu; R T Borchardt
Journal:  Pharm Res       Date:  1990-12       Impact factor: 4.200

7.  Centrally induced hypotension and bradycardia after administration of alpha-methylnoradrenaline into the area of the nucleus tractus solitarii of the rat.

Authors:  W De Jong; F P Nijkamp
Journal:  Br J Pharmacol       Date:  1976-12       Impact factor: 8.739

8.  The influence of SK & F 64139, a phenylethanolamine-N-methyltransferase inhibitor, on centrally mediated cardiovascular effects of alpha-methyldopa and clonidine.

Authors:  M Gerold; G Haeusler
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-12       Impact factor: 3.000

9.  Alpha-methyl-DOPA induced mydriasis in the cat. Relationship between pupillary response and the oculomotor perfusate concentration of methyldopa and its metabolites.

Authors:  T Gherezghiher; M C Koss; H D Christensen
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1983-11       Impact factor: 3.000

10.  Disposition and pharmacodynamics of diuretics and antihypertensive agents in renal disease.

Authors:  B L Mirkin; T P Green; R F O'Dea
Journal:  Eur J Clin Pharmacol       Date:  1980-07       Impact factor: 2.953

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