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Literature DB >> 4176223

Interactions of the complement system with endotoxic lipopolysaccharide: consumption of each of the six terminal complement components.

Abstract

Large amounts of each C'3, C'5, C'6, C'7, C'8, and C'9 were consumed when guinea pig serum was incubated with endotoxic lipopolysaccharide, zymosan, or preformed immune complexes. Since these C' components subserve several of the biological activities which follow the injection of endotoxins into experimental animals, these experiments support the hypothesis that certain biological effects induced by endotoxins may be mediated via the C' system, and may account for some of the known similarity in the reactivities evoked by endotoxins and immune complexes in vivo.

Entities: Chemical Species

Mesh：

Substances：

Year: 1968 PMID： 4176223 PMCID： PMC2138564 DOI： 10.1084/jem.128.5.1049

Source DB: PubMed Journal: J Exp Med ISSN： 0022-1007 Impact factor: 14.307

28 in total

1. LESIONS IN ERYTHROCYTE MEMBRANES CAUSED BY IMMUNE HAEMOLYSIS.

Authors: T BORSOS; R R DOURMASHKIN; J H HUMPHREY
Journal: Nature Date: 1964-04-18 Impact factor: 49.962

2. THE EFFECT OF ADJUVANT AMOUNTS OF ENDOTOXINS ON THE SERUM HEMOLYTIC COMPLEMENT ACTIVITY IN RABBITS.

Authors: D S PEARLMAN; J B SAUERS; D W TALMAGE
Journal: J Immunol Date: 1963-12 Impact factor: 5.422

3. Inactivation of complement by egg albumin; rabbit antiegg albumin.

Authors: G CAVALLO; O J PLESCIA; M HEIDELBERGER
Journal: J Immunol Date: 1958-04 Impact factor: 5.422

4. Properdin system and immunity. II. Interaction of the properdin system with polysaccharides.

Authors: L PILLEMER; M D SCHOENBERG; L BLUM; L WURZ
Journal: Science Date: 1955-09-23 Impact factor: 47.728

5. The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena.

Authors: L PILLEMER; L BLUM; I H LEPOW; O A ROSS; E W TODD; A C WARDLAW
Journal: Science Date: 1954-08-20 Impact factor: 47.728

6. Ultrastructure of the cell wall of Escherichia coli and chemical nature of its constituent layers.

Authors: S De Petris
Journal: J Ultrastruct Res Date: 1967-07

7. Interactions of the complement system with endotoxins from a Salmonella minnesota mutant deficient in O-polysaccharide and heptose.

Authors: S E Mergenhagen; H Gewurz; H A Bladen; A Nowotny; N Kasai; O Lüderitz
Journal: J Immunol Date: 1968-01 Impact factor: 5.422

8. Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum.

Authors: R A Nelson; J Jensen; I Gigli; N Tamura
Journal: Immunochemistry Date: 1966-03

9. Reassociation of purified lipopolysaccharide and phospholipid of the bacterial cell envelope: electron microscopic and monolayer studies.

Authors: L Rothfield; R W Horne
Journal: J Bacteriol Date: 1967-05 Impact factor: 3.490

10. Formation and functional significance of a molecular complex derived from the second and the fourth component of human complement.

Authors: H J Müller-Eberhard; M J Polley; M A Calcott
Journal: J Exp Med Date: 1967-02-01 Impact factor: 14.307

72 in total

9. Interactions of the classical and alternate complement pathway with endotoxin lipopolysaccharide. Effect on platelets and blood coagulation.

Authors: M A Kane; J E May; M M Frank
Journal: J Clin Invest Date: 1973-02 Impact factor: 14.808

10. Inhibition of chemotaxis of neutrophil leukocytes to interleukin-8 by endotoxins of various bacteria.

Authors: L P Bignold; S D Rogers; T M Siaw; J Bahnisch
Journal: Infect Immun Date: 1991-11 Impact factor: 3.441

Interactions of the complement system with endotoxic lipopolysaccharide: consumption of each of the six terminal complement components.

1. LESIONS IN ERYTHROCYTE MEMBRANES CAUSED BY IMMUNE HAEMOLYSIS.

2. THE EFFECT OF ADJUVANT AMOUNTS OF ENDOTOXINS ON THE SERUM HEMOLYTIC COMPLEMENT ACTIVITY IN RABBITS.

3. Inactivation of complement by egg albumin; rabbit antiegg albumin.

4. Properdin system and immunity. II. Interaction of the properdin system with polysaccharides.

5. The properdin system and immunity. I. Demonstration and isolation of a new serum protein, properdin, and its role in immune phenomena.

6. Ultrastructure of the cell wall of Escherichia coli and chemical nature of its constituent layers.

7. Interactions of the complement system with endotoxins from a Salmonella minnesota mutant deficient in O-polysaccharide and heptose.

8. Methods for the separation, purification and measurement of nine components of hemolytic complement in guinea-pig serum.

9. Reassociation of purified lipopolysaccharide and phospholipid of the bacterial cell envelope: electron microscopic and monolayer studies.

10. Formation and functional significance of a molecular complex derived from the second and the fourth component of human complement.

Review 1. Suppression of the immune response by microorganisms.

2. Effects of intravascular clotting on the activation of the complement system: The role of the platelet.

3. The effect of anticomplementary substances on properdin in normal and C2-deficient sera.

4. Effect of pneumococci on blood clotting, platelets, and polymorphonuclear leukocytes.

5. [Relations between complement and blood coagulation (author's transl)].

6. Opsonized streptococcal cell walls cross-link human leukocytes and erythrocytes by complement receptors.

7. Activation of the alternative complement pathway by L-phase variants of gram-positive bacteria.

8. In vivo studies in C4-deficient guinea pigs.

9. Interactions of the classical and alternate complement pathway with endotoxin lipopolysaccharide. Effect on platelets and blood coagulation.

10. Inhibition of chemotaxis of neutrophil leukocytes to interleukin-8 by endotoxins of various bacteria.