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Literature DB >> 415776

Trout hepatic enzyme activation of aflatoxin B1 in a mutagen assay system and the inhibitory effect of PCBs1.

Abstract

In summary, it was demonstrated that the trout PMF may be successfully employed in the Ames mutagen assay method by utilization of proper salts solution and a metabolic preincubation period at 25 degrees C. It has also been observed that, unlike the rat, pretreatment of rainbow trout with various PCBs decrease the mutagen assay response to AFB.

Entities: Chemical Species

Mesh：

Substances：

Year: 1978 PMID： 415776 DOI： 10.1007/bf01685764

Source DB: PubMed Journal: Bull Environ Contam Toxicol ISSN： 0007-4861 Impact factor: 2.151

26 in total

1. PARATHION ACTIVATION BY LIVERS OF AQUATIC AND TERRESTRIAL VERTEBRATES.

Authors: J L POTTER; R D O'BRIEN
Journal: Science Date: 1964-04-03 Impact factor: 47.728

2. Dealkylation of alkoxybiphenyls by trout and frog liver preparations.

Authors: P J Creaven; W H Davies; R T Williams
Journal: Life Sci Date: 1967-01-01 Impact factor: 5.037

3. A comparison between some effects of two pure chlorobiphenyls (2,4',5-trichlorobiphenyl and 2,2',4,4',5,5'-hexachlorobiphenyl) on the hepatic drug metabolizing system in the female mouse.

Authors: J Orberg
Journal: Acta Pharmacol Toxicol (Copenh) Date: 1976-08

4. Aflatoxin B1 metabolism to aflatoxicol and derivatives lethal to Bacillus subtilis GSY 1057 by rainbow trout (Salmo gairdneri) liver.

Authors: G L Schoenhard; D J Lee; S E Howell; N E Pawlowski; L M Libbey; R O Sinnhuber
Journal: Cancer Res Date: 1976-06 Impact factor: 12.701

5. The oxidation of drugs by fishes.

Authors: D R Buhler; M E Rasmusson
Journal: Comp Biochem Physiol Date: 1968-04

6. Effect of aroclor 1016 and 1242 on enzyme systems in the rat.

Authors: F Iverson; D C Villeneuve; D L Grant; G V Hatina
Journal: Bull Environ Contam Toxicol Date: 1975-04 Impact factor: 2.151

7. Comparative effects of commercial Aroclors on rat liver enzyme activities.

Authors: D J Ecobichon; A M Comeau
Journal: Chem Biol Interact Date: 1974-11 Impact factor: 5.192

8. Polychlorinated biphenyls: comparative effects of high and low chlorine containing Aroclors on hepatic mixed function oxidase.

Authors: D R Bickers; L C Harber; A Kappas; A P Alvares
Journal: Res Commun Chem Pathol Pharmacol Date: 1972-05