Literature DB >> 4153578

Gamma-aminobutyric acid effects on pituitary gonadotropin secretion.

J G Ondo.   

Abstract

Gamma-aminobutyric acid (GABA) injected into the third ventricle of male rats promotes the release of pituitary luteinizing hormone (LH) but not follicle-stimulating hormone. When GABA was injected directly into the pituitary it was ineffective in promoting LH release. This evidence suggests that GABA may play a role in controlling the discharge of hypothalamic luteinizing hormone releasing factor.

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Year:  1974        PMID： 4153578     DOI： 10.1126/science.186.4165.738

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  13 in total

Review 1.  Depolarising and hyperpolarising actions of GABA(A) receptor activation on gonadotrophin-releasing hormone neurones: towards an emerging consensus.

Authors:  A E Herbison; S M Moenter
Journal:  J Neuroendocrinol       Date:  2011-07       Impact factor: 3.627

2.  Involvement of endogenous gabaergic system in the modulation of gonadotropin secretion in normal cycling women.

Authors:  G B Melis; V Mais; A M Paoletti; F Beneventi; F D Petacchi; P Fioretti
Journal:  J Endocrinol Invest       Date:  1986-02       Impact factor: 4.256

3.  Evidence for the involvement of a GABA-mediated inhibition in the hypovolaemia-induced vasopressin release.

Authors:  W Knepel; D Nutto; G Hertting
Journal:  Pflugers Arch       Date:  1980-11       Impact factor: 3.657

4.  Inhibitory actions of amino acids in the preoptic-anterior hypothalamus of the rat.

Authors:  M L Mayer
Journal:  Exp Brain Res       Date:  1981       Impact factor: 1.972

5.  Effect of long-term treatment with sodium valproate on gonadotrophin and prolactin secretion in paediatric patients.

Authors:  A Masala; T Meloni; S Alagna; P P Rovasio; S Rassu; G Mele; V Franca
Journal:  Br J Clin Pharmacol       Date:  1981-12       Impact factor: 4.335

Review 6.  Immortalized hypothalamic luteinizing hormone-releasing hormone (LHRH) neurons: a new tool for dissecting the molecular and cellular basis of LHRH physiology.

Authors:  W C Wetsel
Journal:  Cell Mol Neurobiol       Date:  1995-02       Impact factor: 5.046

7.  Selective neuroendocrine effects of low-dose haloperidol in normal adult men.

Authors:  R T Rubin; R E Poland; D O'Connor; P R Gouin; B B Tower
Journal:  Psychopharmacologia       Date:  1976-05-28

8.  Electrophysiological analysis of inhibitory synaptic mechanisms in the preoptic area of the rat.

Authors:  M L Mayer
Journal:  J Physiol       Date:  1981-07       Impact factor: 5.182

9.  Hypothalamic tyrosine hydroxylase activity, plasma gonadotropin and prolactin levels after aminooxyacetic acid in ovariectomized rats.

Authors:  G N Babu; E Vijayan
Journal:  Experientia       Date:  1984-12-15

10.  Involvement of preoptic-anterior hypothalamic GABA neurons in the regulation of pituitary LH and prolactin release.

Authors:  R Lamberts; E Vijayan; M Graf; T Mansky; W Wuttke
Journal:  Exp Brain Res       Date:  1983       Impact factor: 1.972
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