Literature DB >> 4151655

Choreo-athetosis and encephalopathy induced by phenytoin.

D L McLellan, M Swash.   

Abstract

Two patients with intractable epilepsy who had been treated with various combinations of anticonvulsant drugs developed phenytoin encephalopathy. In both patients choreo-athetoid involuntary movements were prominent. Blood phenytoin concentrations were above 30 mug/ml. When phenytoin was given in smaller doses and its level in the blood fell the involuntary movements and other clinical manifestations disappeared.

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Year:  1974        PMID： 4151655      PMCID： PMC1610848          DOI： 10.1136/bmj.2.5912.204

Source DB:  PubMed          Journal:  Br Med J        ISSN： 0007-1447


  7 in total

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6.  Sulthiame (Ospolot) as inhibitor of diphenylhydatoin metabolism.

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  7 in total
  7 in total

1.  Hyperparathyroidism, osteomalacia and peripheral neuropathy in a patient on anticonvulsant therapy.

Authors:  D McCarthy; N Manning; M Drury
Journal:  Ir J Med Sci       Date:  1977-01       Impact factor: 1.568

2.  Involuntary movements caused by phenytoin intoxication in epileptic patients.

Authors:  S Ahmad; J Laidlaw; G W Houghton; A Richens
Journal:  J Neurol Neurosurg Psychiatry       Date:  1975-03       Impact factor: 10.154

3.  Anticonvulsant-induced dyskinesias: a comparison with dyskinesias induced by neuroleptics.

Authors:  D Chadwick; E H Reynolds; C D Marsden
Journal:  J Neurol Neurosurg Psychiatry       Date:  1976-12       Impact factor: 10.154

4.  Phenytoin-induced orofacial dyskinesia. A case report.

Authors:  M Yoshida; S Yamada; Y Ozaki; T Nakanishi
Journal:  J Neurol       Date:  1985       Impact factor: 4.849

5.  Clinical and experimental studies of phenytoin-induced hyperkinesias.

Authors:  P A Nausieda; W C Koller; W J Weiner; H L Klawans
Journal:  J Neural Transm       Date:  1979       Impact factor: 3.575

Review 6.  CNS adverse events associated with antiepileptic drugs.

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7.  Electroencephalography and phenytoin toxicity in mentally retarded epileptic patients.

Authors:  M Iivanainen; M Viukari; A M Seppäläinen; E P Helle
Journal:  J Neurol Neurosurg Psychiatry       Date:  1978-03       Impact factor: 10.154
  7 in total

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