Literature DB >> 4146453

The effect of L-ascorbate on catecholamine biosynthesis.

K J Stone, B H Townsley.   

Abstract

l-Ascorbate stimulates the enzymic hydroxylation of phenylalanine in vitro by recycling tetrahydrobiopterin, which reduces O(2) utilized in the reaction. It is suggested that ascorbate might have a similar function in vivo; this would explain the apparent regulation of tyrosine hydroxylase and tryptophan hydroxylase activities by this vitamin.

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Year:  1973        PMID： 4146453      PMCID： PMC1177509          DOI： 10.1042/bj1310611

Source DB:  PubMed          Journal:  Biochem J        ISSN： 0264-6021            Impact factor:   3.857


  17 in total

1.  The chemical estimation of tyrosine and tyramine.

Authors:  S UDENFRIEND; J R COOPER
Journal:  J Biol Chem       Date:  1952-05       Impact factor: 5.157

2.  Conversion of tryptopan to 5-hydroxytryptophan by phenylalanine hydroxylase.

Authors:  J RENSON; F GOODWIN; H WEISSBACH; S UDENFRIEND
Journal:  Biochem Biophys Res Commun       Date:  1961-10-23       Impact factor: 3.575

3.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

4.  Phenylalanine-hydroxylating system in the human fetus at different developmental ages.

Authors:  A Jakubovic
Journal:  Biochim Biophys Acta       Date:  1971-06-22

5.  A direct assay for liver phenylalanine hydroxylase.

Authors:  C Bublitz
Journal:  Biochim Biophys Acta       Date:  1969-11-04

6.  A protein that stimulates rat liver phenylalanine hydroxylase.

Authors:  S Kaufman
Journal:  J Biol Chem       Date:  1970-09-25       Impact factor: 5.157

7.  Effect of ascorbic acid on hydroxylase activity. I. Stimulation of tyrosine hydroxylase and tryptophan-5-hydroxylase activities by ascorbic acid.

Authors:  Y Nakashima; R Suzue; H Sanada; S Kawada
Journal:  J Vitaminol (Kyoto)       Date:  1970-12-10

8.  Defect in synthesis of epinephrine in premature infants with tyrosinemia.

Authors:  I J Light; J M Sutherland; J Loggie; H Berry
Journal:  Metabolism       Date:  1971-03       Impact factor: 8.694

9.  Phenylalanine hydroxylase of Macaca irus. Purification of two components of the enzyme.

Authors:  R G Cotton
Journal:  Biochim Biophys Acta       Date:  1971-04-14

10.  Rat liver phenylalanine hydroxylase. A method for the measurement of activity, with particular reference to the distinctive features of the enzyme and the pteridine cofactor.

Authors:  K H Nielsen
Journal:  Eur J Biochem       Date:  1969-01
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  8 in total

1.  Ascorbic acid in fetal human brain.

Authors:  B P Adlard; S W De Souza; S Moon
Journal:  Arch Dis Child       Date:  1974-04       Impact factor: 3.791

2.  Ascorbic acid efficiently enhances neuronal synthesis of norepinephrine from dopamine.

Authors:  James M May; Zhi-Chao Qu; Rafal Nazarewicz; Sergey Dikalov
Journal:  Brain Res Bull       Date:  2012-09-26       Impact factor: 4.077

3.  Intravenous ascorbic acid to prevent and treat cancer-associated sepsis?

Authors:  Thomas E Ichim; Boris Minev; Todd Braciak; Brandon Luna; Ron Hunninghake; Nina A Mikirova; James A Jackson; Michael J Gonzalez; Jorge R Miranda-Massari; Doru T Alexandrescu; Constantin A Dasanu; Vladimir Bogin; Janis Ancans; R Brian Stevens; Boris Markosian; James Koropatnick; Chien-Shing Chen; Neil H Riordan
Journal:  J Transl Med       Date:  2011-03-04       Impact factor: 5.531

4.  The role of tetrahydrofolate dehydrogenase in the hepatic supply of tetrahydrobiopterin in rats.

Authors:  K J Stone
Journal:  Biochem J       Date:  1976-07-01       Impact factor: 3.857

5.  Behavioral and monoamine changes following severe vitamin C deficiency.

Authors:  Margaret S Ward; Jonathan Lamb; James M May; Fiona E Harrison
Journal:  J Neurochem       Date:  2012-11-30       Impact factor: 5.372

6.  Relationships between dietary ascorbic acid status and deficiency, weight gain and brain neurotransmitter levels in juvenile rainbow trout,Salmo gairdneri.

Authors:  W L Johnston; E Macdonald; J W Hilton
Journal:  Fish Physiol Biochem       Date:  1989-11       Impact factor: 2.794

Review 7.  Vitamin C in the critically ill - indications and controversies.

Authors:  Christoph S Nabzdyk; Edward A Bittner
Journal:  World J Crit Care Med       Date:  2018-10-16

8.  Two known therapies could be useful as adjuvant therapy in critical patients infected by COVID-19.

Authors:  A Hernández; P J Papadakos; A Torres; D A González; M Vives; C Ferrando; J Baeza
Journal:  Rev Esp Anestesiol Reanim (Engl Ed)       Date:  2020-04-14
  8 in total

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