Literature DB >> 4141598

In vitro system for production of mouse mammary tumor virus.

D L Fine, L O Arthur, J K PLOWMAN, E A Hillman, F Klein.   

Abstract

An in vitro system for production, purification, and concentration of mouse mammary tumor virus is described. Monolayer cultures of C(3)H mouse mammary tumor cells propagated at 34 C in roller bottles in the presence of dexamethasone, a glucocorticoid hormone, release B-type particles which possess ribonucleic acid and a ribonucleic acid-dependent deoxyribonucleic acid polymerase. One thousandfold concentration by ultracentrifugation with subsequent gradient fractionation yielded > 7 x 10(10) particles per ml in the 1.16- to 1.18-g/ml region. Mouse mammary tumor virus produced in this system was free of detectable C-type virus.

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Year:  1974        PMID： 4141598      PMCID： PMC186879          DOI： 10.1128/am.28.6.1040-1046.1974

Source DB:  PubMed          Journal:  Appl Microbiol        ISSN： 0003-6919


  22 in total

1.  Some physical and biological characteristics of the mouse mammary tumor virus.

Authors:  D H Moore; N H Sarkar; J Charney; B Kramarsky
Journal:  Cancer Res       Date:  1973-01       Impact factor: 12.701

2.  Immunological characterization of primate C-type virus reverse transcriptases.

Authors:  E M Scolnick; W P Parks; G J Todaro; S A Aaronson
Journal:  Nat New Biol       Date:  1972-01-12

3.  Stimulation of mammary tumor virus production in a mouse mammary tumor cell line.

Authors:  E Y Lasfargues; B Kramarsky; N H Sarkar; J C Lasfargues; N Pillsbury; D H Moore
Journal:  Cancer Res       Date:  1970-04       Impact factor: 12.701

4.  Enhanced production of mouse mammary tumor virus in dexamethasone-treated, 5-iododeoxyuridine-stimulated mammary tumor cell cultures.

Authors:  D L Fine; J K Plowman; S P Kelley; L O Arthur; E A Hillman
Journal:  J Natl Cancer Inst       Date:  1974-06       Impact factor: 13.506

5.  Observations on a cell line producing mammary tumor virus.

Authors:  J A Sykes; J Whitescarver; L Briggs
Journal:  J Natl Cancer Inst       Date:  1968-12       Impact factor: 13.506

6.  In vitro cultivation of the mouse mammary tumor virus: replication of MTV in tissue culture.

Authors:  R D Cardiff; P R Blair; K B DeOme
Journal:  Virology       Date:  1968-10       Impact factor: 3.616

7.  Isopycnic zonal centrifugation and characterization of the mouse mammary tumor virus (MTV) in different gradient solutions.

Authors:  J S Manning; A J Hackett; R D Cardiff; H C Mel; P B Blair
Journal:  Virology       Date:  1970-04       Impact factor: 3.616

8.  Rapid semiquantitative method for screening large numbers of virus samples by negative staining electron microscopy.

Authors:  J H Monroe; P M Brandt
Journal:  Appl Microbiol       Date:  1970-08

9.  Rapid detection of mycoplasma-infected cell cultures.

Authors:  G J Todaro; S A Aaronson; E Rands
Journal:  Exp Cell Res       Date:  1971-03       Impact factor: 3.905

10.  Immunochemical characterization of two major polypeptides from murine mammary tumor virus.

Authors:  W P Parks; R S Howk; E M Scolnick; S Oroszlan; R V Gilden
Journal:  J Virol       Date:  1974-06       Impact factor: 5.103
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  23 in total

1.  Rescue of endogenous 30S retroviral sequences from mouse cells by baboon type C virus.

Authors:  S A Sherwin; U R Rapp; R E Benveniste; A Sen; G J Todaro
Journal:  J Virol       Date:  1978-05       Impact factor: 5.103

2.  Identification of the Mtv-2 gene responsible for the early appearance of mammary tumors in the GR mouse by nucleic acid hybridization.

Authors:  R Michalides; L van Deemter; R R Nuss; R van Nie
Journal:  Proc Natl Acad Sci U S A       Date:  1978-05       Impact factor: 11.205

3.  Sensitive reverse transcriptase assay to detect and quantitate human immunodeficiency virus.

Authors:  M H Lee; K Sano; F E Morales; D T Imagawa
Journal:  J Clin Microbiol       Date:  1987-09       Impact factor: 5.948

4.  Large-scale production of mouse mammary tumor virus in the absence of endogenous murine leukemia virus.

Authors:  C V Benton; J S Harshman; O R Robinson; G P Shibley
Journal:  Appl Environ Microbiol       Date:  1979-01       Impact factor: 4.792

5.  New method for large-scale growth; and concentration of the Epstein-Barr viruses.

Authors:  G P Shibley; M Manousos; K Munch; I Zelljadt; L Fisher; S Mayyasi; K Harewood; R Stevens; K E Jensen
Journal:  Appl Environ Microbiol       Date:  1980-12       Impact factor: 4.792

6.  Establishment of a C3Hf mammary tumor cell line expressing endogenous mouse mammary tumor virus: antigenic and genetic relationships of this virus with highly oncogenic mouse mammary tumor viruses.

Authors:  L O Arthur; G G Lovinger; G Schochetman
Journal:  J Virol       Date:  1979-12       Impact factor: 5.103

7.  Reverse transcriptase activity per virion for avian myeloblastosis virus and Rauscher murine leukemia virus.

Authors:  L F Liebes; M A Rich; J J McCormick; I Salmeen; L Rimai
Journal:  J Virol       Date:  1976-04       Impact factor: 5.103

8.  Purification of immature cores of mouse mammary tumor virus and immunolocalization of protein domains.

Authors:  L Menéndez-Arias; C Risco; P Pinto da Silva; S Oroszlan
Journal:  J Virol       Date:  1992-09       Impact factor: 5.103

9.  Detection and characterization of mouse mammary tumor virus cell surface antigens: estimation of antigen abundance by protein A assay.

Authors:  A H Callis; E M Ritzi
Journal:  J Virol       Date:  1980-09       Impact factor: 5.103

10.  Isolation of the mouse mammary tumor virus sequences not transmitted as germinal provirus in the C3H and RIII mouse strains.

Authors:  W Drohan; R Kettmann; D Colcher; J Schlom
Journal:  J Virol       Date:  1977-03       Impact factor: 5.103
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