Literature DB >> 4139716

Inhibition of murine leukemia virus production in chronically infected AKR cells: a novel effect of interferon.

R M Friedman, J M Ramseur.   

Abstract

Treatment of AKR cells that had spontaneously become procedures of a murine leukemia virus with a partially purified mouse interferon (> 5 x 10(7) international mouse reference units per mg of protein) inhibited endogenous virus production. This inhibitory effect decreased over a 72-hr period in a manner similar to interferon-induced antiviral activity directed against vesicular stomatitis virus in AKR cells. Despite the inhibitory effect of interferon on infectious murine leukemia virus and viral reverse transcriptase (RNA-dependent DNA polymerase) titers in the culture fluids, intracellular levels of viral groups-specific antigens were significantly increased. These results suggest that interferon treatment in AKR cells inhibited the assembly or release of the virus.

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Year:  1974        PMID： 4139716      PMCID： PMC433810          DOI： 10.1073/pnas.71.9.3542

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  10 in total

1.  Influence of interferon on virus particle formation in different oncornavirus carrier cell lines.

Authors:  A Billiau; H Sobis; P De Somer
Journal:  Int J Cancer       Date:  1973-11-15       Impact factor: 7.396

2.  Nucleic acid and proteins isolated from a strain of murine sarcoma virus (MSV-O).

Authors:  A E Horvath; R M Friedman
Journal:  Proc Soc Exp Biol Med       Date:  1971-07

3.  Inhibitory effect of interferon on murine sarcoma and leukaemia virus infection in vitro.

Authors:  P S Sarma; G Shiu; S Baron; R J Huebner
Journal:  Nature       Date:  1969-08-23       Impact factor: 49.962

4.  Purification of mouse interferon by affinity chromatography on anti-interferon globulin-sepharose.

Authors:  C A Ogburn; K Berg; K Paucker
Journal:  J Immunol       Date:  1973-10       Impact factor: 5.422

5.  Plaque assay techniques for murine leukemia viruses.

Authors:  W P Rowe; W E Pugh; J W Hartley
Journal:  Virology       Date:  1970-12       Impact factor: 3.616

6.  Radioimmunoassay of mammalian type C viral proteins. I. Species specific reactions of murine and feline viruses.

Authors:  E M Scolnick; W P Parks; D M Livingston
Journal:  J Immunol       Date:  1972-09       Impact factor: 5.422

7.  RNA dependent DNA polymerase activity in mammalian cells.

Authors:  E M Scolnick; S A Aaronson; G J Todaro; W P Parks
Journal:  Nature       Date:  1971-01-29       Impact factor: 49.962

8.  Mechanism of interferon action: inhibition of viral messenger ribonucleic acid translation in L-cell extracts.

Authors:  R M Friedman; D H Metz; R M Esteban; D R Tovell; L A Ball; I M Kerr
Journal:  J Virol       Date:  1972-12       Impact factor: 5.103

9.  Evidence that the AKR murine-leukemia-virus genome is complete in DNA of the high-virus AKR mouse and incomplete in the DNA of the "virus-negative" NIH mouse.

Authors:  S K Chattopadhyay; D R Lowy; N M Teich; A S Levine; W P Rowe
Journal:  Proc Natl Acad Sci U S A       Date:  1974-01       Impact factor: 11.205

10.  Interferon and transcription of early virus-specific RNA in cells infected with simian virus 40.

Authors:  M N Oxman; M J Levin
Journal:  Proc Natl Acad Sci U S A       Date:  1971-02       Impact factor: 11.205
  10 in total
  30 in total

Review 1.  Antiviral activity of interferons.

Authors:  R M Friedman
Journal:  Bacteriol Rev       Date:  1977-09

Review 2.  Clinical uses of interferons.

Authors:  Robert M Friedman
Journal:  Br J Clin Pharmacol       Date:  2007-12-07       Impact factor: 4.335

3.  Synthesis of type C virus particles from murine-cultured cells induced by iododeoxyuridine. V. Effect of interferon and its interaction with dexamethasone.

Authors:  A M Wu; A Schultz; R C Gallo
Journal:  J Virol       Date:  1976-07       Impact factor: 5.103

4.  Physical, morphological, and biochemical alterations in the membrane of AKR mouse cells after interferon treatment.

Authors:  E H Chang; F T Jay; R M Friedman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

5.  Interferon alters the pattern of secreted proteins from Ehrlich ascites-tumour cells.

Authors:  S Tominaga; K Tominaga
Journal:  Biochem J       Date:  1989-07-01       Impact factor: 3.857

Review 6.  Interferons: anti-neoplastic drugs?

Authors:  H Strander
Journal:  Blut       Date:  1977-09-18

7.  Variable infection of Vero cells and homologous interference after co-cultivation with HeLa cells with persistent defective infection by Edmonston measles virus.

Authors:  R Rustigian; S H Winston; R W Darlington
Journal:  Infect Immun       Date:  1979-03       Impact factor: 3.441

8.  Interferon-directed inhibition of chronic murine leukemia virus production in cell cultures: lack of effect on intracellular viral markers.

Authors:  R M Friedman; E H Chang; J M Ramseur; M W Myers
Journal:  J Virol       Date:  1975-09       Impact factor: 5.103

9.  Receptor mediated pathways for interferon action: in vivo implications.

Authors:  K E Mogensen; M T Bandu; F Vignaux; G Uze; P Eid
Journal:  Med Oncol Tumor Pharmacother       Date:  1984

10.  Treatment of hepatitis C infections with interferon: a historical perspective.

Authors:  Robert M Friedman; Sara Contente
Journal:  Hepat Res Treat       Date:  2010-09-06
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