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Literature DB >> 4136566

Biophysical differentiation between lymphocytes from healthy donors, patients with malignant diseases and other disorders.

Abstract

Changes in the structuredness of the cytoplasmic matrix (SCM) of human lymphocytes induced by PHA, CaBP and EF were studied with the technique of fluorescence polarization. The study suggests that the SCM test may offer a new and fast technique for the detection of malignant growth.

Entities: Disease Gene Species

Mesh：

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Year: 1974 PMID： 4136566 PMCID： PMC2009021 DOI： 10.1038/bjc.1974.81

Source DB: PubMed Journal: Br J Cancer ISSN： 0007-0920 Impact factor: 7.640

5 in total

1. Clinical evaluation of the Makari tumour skin test.

Authors: D E Tee
Journal: Br J Cancer Suppl Date: 1973-08

2. Rapid preparation of lymphocytes for tissue-typing.

Authors: R Harris; E O Ukaejiofo
Journal: Lancet Date: 1969-08-09 Impact factor: 79.321

3. Structuredness of the cytoplasmic matrix and Michaelis-Menten constants for the hydrolysis of FDA during the cell cycle in Chinese hamster ovary cells.

Authors: L Cercek; B Cercek; C H Ockey
Journal: Biophysik Date: 1973

4. Lymphocyte sensitisation: an in-vitro test for cancer?

Authors: E J Field; E A Caspary
Journal: Lancet Date: 1970-12-26 Impact factor: 79.321

Review 5. Foetal antigens and their role in the diagnosis and clinical management of human neoplasms: a review.

Authors: D J Laurence; A M Neville
Journal: Br J Cancer Date: 1972-10 Impact factor: 7.640

5 in total

20 in total

1. The inhibitory effect of ionophore A23187 on the hydrolysis of fluorescein diacetate by human lymphocytes [proceedings].

Authors: P W Mullen
Journal: Br J Pharmacol Date: 1979-07 Impact factor: 8.739

2. Changes in the structuredness of cytoplasmic matrix (SCM) induced in mixed lymphocyte interactions.

Authors: L Cercek; B Cercek
Journal: Radiat Environ Biophys Date: 1976-03-30 Impact factor: 1.925

3. Comments on the fluorescein excitation and emission polarization spectra in living cells.

Authors: G B Price; R G Miller
Journal: Biophys J Date: 1979-11 Impact factor: 4.033

Review 4. Human tumour-associated and tumour-specific antigens: some concepts in relation to clinical oncology.

Authors: A M Neville; A M Mackay; J Westwood; C Turberville; D J Laurence
Journal: J Clin Pathol Suppl (Assoc Clin Pathol) Date: 1975

5. Induction of PHA response in mouse bone marrow cells by thymic extracts as studied by changes in the structuredness of cytoplasmic matrix.

Authors: L Cercek; P Milenkovic; B Cercek; L G Lajtha
Journal: Immunology Date: 1975-11 Impact factor: 7.397

Biophysical differentiation between lymphocytes from healthy donors, patients with malignant diseases and other disorders.

1. Clinical evaluation of the Makari tumour skin test.

2. Rapid preparation of lymphocytes for tissue-typing.

3. Structuredness of the cytoplasmic matrix and Michaelis-Menten constants for the hydrolysis of FDA during the cell cycle in Chinese hamster ovary cells.

4. Lymphocyte sensitisation: an in-vitro test for cancer?

Review 5. Foetal antigens and their role in the diagnosis and clinical management of human neoplasms: a review.

1. The inhibitory effect of ionophore A23187 on the hydrolysis of fluorescein diacetate by human lymphocytes [proceedings].

2. Changes in the structuredness of cytoplasmic matrix (SCM) induced in mixed lymphocyte interactions.

3. Comments on the fluorescein excitation and emission polarization spectra in living cells.

Review 4. Human tumour-associated and tumour-specific antigens: some concepts in relation to clinical oncology.

5. Induction of PHA response in mouse bone marrow cells by thymic extracts as studied by changes in the structuredness of cytoplasmic matrix.

6. PAL-test for malignant disease.

7. Flow cytometric measurement of the polarization of fluorescence from intracellular fluorescein in mammalian cells.

Review 8. Fluorescent probes to detect lymphocyte activation.

9. Changes in the SCM response ratio (RRscm) after surgical removal of malignant tissue.

10. Clinical evaluation of the macrophage electrophoretic mobility test for cancer.