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Literature DB >> 4135071

Alpha-chain disease with clinical, immunological, and histological recovery.

O N Manousos, J C Economidou, D E Georgiadou, K G Pratsika-Ougourloglou, S J Hadziyannis, G E Merikas, K Henry, W F Doe.

Abstract

Clinical, immunological, and histological recovery in a patient with alpha-chain disease is described. The patient, a 27-year-old Greek man, presented with severe steatorrhoea, abdominal pain, oedema, and hypogammaglobulinaemia. Treatment with tetracycline produced only temporary remission. Intermittent therapy with prednisone and cyclophosphamide together with antibiotics was followed by clinical recovery, return of histological appearances of the small intestine to normal, and disappearance of free alpha-chain protein from the serum. The patient remained well one year later without treatment.

Entities: Chemical Disease Gene Species

Mesh：

Substances：

Year: 1974 PMID： 4135071 PMCID： PMC1610468 DOI： 10.1136/bmj.2.5916.409

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

7 in total

7. Alpha heavy chain disease lacking secretory alpha chain, with cobblestone appearance of the small intestine and duodenal ulcer demonstrated by endoscopy.

Authors: T Hibi; H Asakura; K Kobayashi; Y Munakata; S Kano; M Tsuchiya; T Teramoto; Y Uematsu
Journal: Gut Date: 1982-05 Impact factor: 23.059

7 in total

Alpha-chain disease with clinical, immunological, and histological recovery.

1. Abdominal lymphoma presenting with malabsorption.

2. Alpha-chain disease: a new immunoglobulin abnormality.

3. Alpha heavy chain disease. A variant of Mediterranean lymphoma.

4. Immunochemical quantitation of antigens by single radial immunodiffusion.

5. [Mediterranean lymphoma with alpha chain disease. Triple chemical anatomic and immunological remission].

6. Alpha chain disease.

7. Five cases of alpha chain disease.

1. [Heavy chain disease: humoral and cellular findings in six patients with mu chain disease (author's transl)].

2. Alpha heavy chain disease (report of 18 cases from Iraq).

3. Alpha-chain disease with localized plasmacytoma of the intestine. Immunoperoxidase study.

4. Alpha-chain disease in an Englishman.

5. Morphological methods in the study of the gut immune system in man.

6. alpha-Chain disease causing kaliopenic nephropathy and fatal intestinal perforations.

7. Alpha heavy chain disease lacking secretory alpha chain, with cobblestone appearance of the small intestine and duodenal ulcer demonstrated by endoscopy.