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Literature DB >> 4135032

Escherichia coli antibody: a screening test for immunodeficiency.

Abstract

Six patients suffering from recurrent chest infections were found to lack antibodies to a pooled antigen obtained from six different serotypes of commensal Escherichia coli bacteria. All had normal serum IgG concentrations, but five subsequently benefited from regular gammaglobulin injections. We suggest that the absence of such E. coli antibodies usually indicates a clinically significant defect in antibody production. This simple screening test is of use in the diagnosis of primary and secondary immunodeficiency disorders.

Entities: Disease Species

Mesh：

Substances：

Year: 1974 PMID： 4135032 PMCID： PMC1611368 DOI： 10.1136/bmj.3.5922.16

Source DB: PubMed Journal: Br Med J ISSN： 0007-1447

5 in total

1. Evidence for the existence of two functionally distinct types of cells which regulate the antibody response to type 3 pneumococcal polysaccharide.

Authors: P J Baker; P W Stashak; D F Amsbaugh; B Prescott; R F Barth
Journal: J Immunol Date: 1970-12 Impact factor: 5.422

2. Studies of urinary tract infections in infancy and childhood. IX. Determination of E. coli antibodies by a polyvalent antigen.

Authors: H J Andersen
Journal: Acta Paediatr Scand Date: 1967-11

3. Antibiodies of the IgG, IgM, and IgA classes in newborn and adult sera reactive with gram-negative bacteria.

Authors: I R Cohen; L C Norins
Journal: J Clin Invest Date: 1968-05 Impact factor: 14.808

4. An international reference preparation for human serum immunoglobulins G, A and M: content of immunoglobulins by weight.

Authors: D S Rowe; B Grab; S G Anderson
Journal: Bull World Health Organ Date: 1972 Impact factor: 9.408

5. ASSOCIATION OF "NATURAL" ANTIBODIES TO GRAM-NEGATIVE BACTERIA WITH THE GAMMA-1-MACROGLOBULINS.

Authors: J G MICHAEL; F S ROSEN
Journal: J Exp Med Date: 1963-10-01 Impact factor: 14.307

5 in total

17 in total

1. Adenosine deaminase activity in erythrocytes, lymphocytes, polymorphonuclear neutrophil leucocytes and cultured cells: a possible role in the immune response.

Authors: A Adams; R A Harkness; J G McVie
Journal: J Inherit Metab Dis Date: 1978 Impact factor: 4.982

9. Differences in intrahepatic portal-systemic shunting in alcoholic and nonalcoholic liver disease as assessed by liver scan, portal pressure, and E. coli antibodies.

Authors: D R Triger; T D Boyer; A G Redeker; T B Reynolds; A D Waxman
Journal: Dig Dis Sci Date: 1979-07 Impact factor: 3.199

10. Antimicrobial proteins in sterilised human milk.

Authors: M Raptopoulou-Gigi; K Marwick; D B McClelland
Journal: Br Med J Date: 1977-01-01

Escherichia coli antibody: a screening test for immunodeficiency.

1. Evidence for the existence of two functionally distinct types of cells which regulate the antibody response to type 3 pneumococcal polysaccharide.

2. Studies of urinary tract infections in infancy and childhood. IX. Determination of E. coli antibodies by a polyvalent antigen.

3. Antibiodies of the IgG, IgM, and IgA classes in newborn and adult sera reactive with gram-negative bacteria.

4. An international reference preparation for human serum immunoglobulins G, A and M: content of immunoglobulins by weight.

5. ASSOCIATION OF "NATURAL" ANTIBODIES TO GRAM-NEGATIVE BACTERIA WITH THE GAMMA-1-MACROGLOBULINS.

1. Adenosine deaminase activity in erythrocytes, lymphocytes, polymorphonuclear neutrophil leucocytes and cultured cells: a possible role in the immune response.

2. Immunological and purine enzyme studies on hyperuricaemic and normouricaemic patients with Down's syndrome.

3. Severe selective IgM deficiency.

4. Recovery of antibody production after HIV infection in 'common' variable hypogammaglobulinaemia.

5. A case of hereditary combined deficiency of complement components C6 and C7 in man.

6. Evaluation of test immunisation in the assessment of antibody deficiency syndromes.

7. Autoimmune blood dyscrasias in five patients with hypogammaglobulinemia: response of neutropenia to vincristine.

8. Effect of in vitro treatment with reducing drugs on structure and function of human secretory immunoglobulin A.

9. Differences in intrahepatic portal-systemic shunting in alcoholic and nonalcoholic liver disease as assessed by liver scan, portal pressure, and E. coli antibodies.

10. Antimicrobial proteins in sterilised human milk.