Literature DB >> 14067909

ASSOCIATION OF "NATURAL" ANTIBODIES TO GRAM-NEGATIVE BACTERIA WITH THE GAMMA-1-MACROGLOBULINS.

J G MICHAEL, F S ROSEN.   

Abstract

"Natural" antibodies to representative species of Enterobacteriaceae were found to be principally associated with the gamma(1)-macroglobulin prepared from Cohn fraction III-I of pooled human plasma. The amount of antibodies present was estimated by measuring the bactericidal, hemagglutinating, mouse-protective, and opsonophagocytic activities of this fraction. Comparison with the antibody activity of gamma(2)-globulin of Cohn fraction II showed that up to 100 times more antibody activity on a weight basis was present in the macroglobulin fraction. These findings suggest that differences between natural and immune antibody result from the physicochemical properties of 2 different classes of immune globulin.

Entities:  

Keywords:  ANTIGEN-ANTIBODY REACTIONS; ESCHERICHIA COLI; EXPERIMENTAL LAB STUDY; GAMMA GLOBULIN; HEMAGGLUTINATION; KLEBSIELLA; MICE; PHAGOCYTOSIS; PSEUDOMONAS AERUGINOSA; SALMONELLA TYPHOSA; SERUM GLOBULINS; SHIGELLA

Mesh：

Substances：

Year:  1963        PMID： 14067909      PMCID： PMC2137662          DOI： 10.1084/jem.118.4.619

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  9 in total

1.  Transient 19S gammaglobulin deficiency in the newborn infant, and its significance.

Authors:  D GITLIN; F S ROSEN; J G MICHAEL
Journal:  Pediatrics       Date:  1963-02       Impact factor: 7.124

2.  Partial purification of opsonins in pig serum to a strain of salmonella typhimurium.

Authors:  D ROWLEY; C R JENKIN
Journal:  Immunology       Date:  1962-09       Impact factor: 7.397

3.  Study on antibodies against enteric pathogens in human gamma globulin.

Authors:  E NETER; A M DRISLANE; A H HARRIS; E A GORZYNSKI
Journal:  Am J Public Health Nations Health       Date:  1959-08

4.  The adsorption of bacterial polysaccharides by erythrocytes.

Authors:  D A DAVIES; M J CRUMPTON; I A MACPHERSON; A M HUTCHISON
Journal:  Immunology       Date:  1958-04       Impact factor: 7.397

5.  Studies on the immunotherapy of bacterial infections. I. The comparative effectiveness of human gamma-globulin against various bacterial species in mice.

Authors:  M W FISHER; M C MANNING
Journal:  J Immunol       Date:  1958-07       Impact factor: 5.422

6.  Agammaglobulinemia, congenital, acquired and transient forms.

Authors:  D GITLIN; C A JANEWAY
Journal:  Prog Hematol       Date:  1956

7.  CHEMICAL, CLINICAL, AND IMMUNOLOGICAL STUDIES ON THE PRODUCTS OF HUMAN PLASMA FRACTIONATION. X. THE CONCENTRATIONS OF CERTAIN ANTIBODIES IN GLOBULIN FRACTIONS DERIVED FROM HUMAN BLOOD PLASMA.

Authors:  J F Enders
Journal:  J Clin Invest       Date:  1944-07       Impact factor: 14.808

8.  The macroglobulins.

Authors:  F S ROSEN
Journal:  N Engl J Med       Date:  1962-09-13       Impact factor: 91.245

9.  Studies on natural antibodies to gram-negative bacteria.

Authors:  J G MICHAEL; J L WHITBY; M LANDY
Journal:  J Exp Med       Date:  1962-01-01       Impact factor: 14.307
  9 in total
  41 in total

1.  QUANTITATIVE STUDIES OF FEBRILE TOLERANCE AND LEVELS OF SPECIFIC ANTIBODY EVOKED BY BACTERIAL ENDOTOXIN.

Authors:  J H MULHOLLAND; S M WOLFF; A L JACKSON; M LANDY
Journal:  J Clin Invest       Date:  1965-06       Impact factor: 14.808

2.  The immunological system of the child: part I: development of immunity in the child.

Authors:  C A Janeway
Journal:  Arch Dis Child       Date:  1966-08       Impact factor: 3.791

3.  Bacterial lipopolysaccharide (LPS)-specific antibodies in commercial human immunoglobulin preparations: superior antibody content of an IgM-enriched product.

Authors:  M Trautmann; T K Held; M Susa; M A Karajan; A Wulf; A S Cross; R Marre
Journal:  Clin Exp Immunol       Date:  1998-01       Impact factor: 4.330

Review 4.  Immunotherapeutic advances in the treatment of gram-negative bacterial sepsis.

Authors:  D L Dunn
Journal:  World J Surg       Date:  1987-04       Impact factor: 3.352

5.  Study of live typhoid vaccine in chimpanzees.

Authors:  B Cvjetanović; D M Mel; O Felsenfeld
Journal:  Bull World Health Organ       Date:  1970       Impact factor: 9.408

6.  Serum sensitivity of a Pseudomonas aeruginosa mucoid strain.

Authors:  N L Schiller; M J Alazard; R S Borowski
Journal:  Infect Immun       Date:  1984-09       Impact factor: 3.441

7.  Bacterial blocking activity of specific IgG in chronic Pseudomonas aeruginosa infection.

Authors:  R M Guttman; B A Waisbren
Journal:  Clin Exp Immunol       Date:  1975-01       Impact factor: 4.330

8.  Immunoelectron microscopic localization of lipopolysaccharides in the cell wall of Bacteroides oralis and Fusobacterium nucleatum.

Authors:  G Dahlén; H Nygren; H A Hannsson
Journal:  Infect Immun       Date:  1978-01       Impact factor: 3.441

9.  THE FORMATION AND PROPERTIES OF POLIOVIRUS-NEUTRALIZING ANTIBODY. IV. NORMAL ANTIBODY AND EARLY IMMUNE ANTIBODY OF RABBIT ORIGIN: A COMPARISON OF BIOLOGICAL AND PHYSICOCHEMICAL PROPERTIES.

Authors:  S E SVEHAG
Journal:  J Exp Med       Date:  1964-04-01       Impact factor: 14.307

10.  Escherichia coli antibody: a screening test for immunodeficiency.

Authors:  A D Webster; T Efter; G L Asherson
Journal:  Br Med J       Date:  1974-07-06
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